from frst import vcf_to_sfs import math if __name__ == "__main__": sfs_folded_hir = {0: 575935, 1: 346313, 2: 220539, 3: 130150, 4: 69989, 5: 33768, 6: 41031} n = len(sfs_folded_hir.values()) pi = 0 s_prime = 0 for i in range(1, n-1): pi += i * (n-1) * sfs_folded_hir[i-1] / math.comb(n, 2) #s_prime += math.comb() * math.comb() / math.comb() print(pi)