HEADER HYDROLASE 17-MAY-76 1EST TITLE THE ATOMIC STRUCTURE OF CRYSTALLINE PORCINE PANCREATIC ELASTASE AT 2.5 TITLE 2 ANGSTROMS RESOLUTION. COMPARISONS WITH THE STRUCTURE OF ALPHA- TITLE 3 CHYMOTRYPSIN COMPND MOL_ID: 1; COMPND 2 MOLECULE: PORCINE PANCREATIC ELASTASE; COMPND 3 CHAIN: A; COMPND 4 EC: 3.4.21.36; COMPND 5 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: SUS SCROFA; SOURCE 3 ORGANISM_COMMON: PIG; SOURCE 4 ORGANISM_TAXID: 9823 KEYWDS HYDROLASE (SERINE PROTEINASE), HYDROLASE EXPDTA X-RAY DIFFRACTION AUTHOR L.SAWYER,D.M.SHOTTON,H.C.WATSON REVDAT 13 24-AUG-11 1EST 1 HEADER HET HETATM HETNAM REVDAT 13 2 1 LINK REMARK VERSN REVDAT 12 24-FEB-09 1EST 1 VERSN REVDAT 11 01-APR-03 1EST 1 JRNL REVDAT 10 16-OCT-87 1EST 1 SOURCE JRNL REVDAT 9 30-SEP-83 1EST 1 REVDAT REVDAT 8 15-JAN-82 1EST 1 REMARK REVDAT 7 20-APR-81 1EST 1 HELIX REVDAT 6 31-DEC-80 1EST 1 REMARK REVDAT 5 25-MAY-78 1EST 1 JRNL REVDAT 4 01-NOV-77 1EST 1 COMPND SOURCE AUTHOR REMARK REVDAT 4 2 1 FORMUL SSBOND REVDAT 3 13-JUN-77 1EST 1 HET REVDAT 2 03-JAN-77 1EST 2 CONECT REVDAT 1 27-MAY-76 1EST 0 JRNL AUTH L.SAWYER,D.M.SHOTTON,J.W.CAMPBELL,P.L.WENDELL,H.MUIRHEAD, JRNL AUTH 2 H.C.WATSON,R.DIAMOND,R.C.LADNER JRNL TITL THE ATOMIC STRUCTURE OF CRYSTALLINE PORCINE PANCREATIC JRNL TITL 2 ELASTASE AT 2.5 A RESOLUTION: COMPARISONS WITH THE STRUCTURE JRNL TITL 3 OF ALPHA-CHYMOTRYPSIN. JRNL REF J.MOL.BIOL. V. 118 137 1978 JRNL REFN ISSN 0022-2836 JRNL PMID 628010 JRNL DOI 10.1016/0022-2836(78)90412-6 REMARK 1 REMARK 1 REFERENCE 1 REMARK 1 AUTH L.SAWYER,D.M.SHOTTON,H.C.WATSON REMARK 1 TITL ATOMIC COORDINATES FOR TOSYL-ELASTASE REMARK 1 REF BIOCHEM.BIOPHYS.RES.COMMUN. V. 53 944 1973 REMARK 1 REFN ISSN 0006-291X REMARK 1 REFERENCE 2 REMARK 1 AUTH D.M.SHOTTON,B.S.HARTLEY REMARK 1 TITL AMINO-ACID SEQUENCE OF PORCINE PANCREATIC ELASTASE AND ITS REMARK 1 TITL 2 HOMOLOGIES WITH OTHER SERINE PROTEINASES REMARK 1 REF NATURE V. 225 802 1970 REMARK 1 REFN ISSN 0028-0836 REMARK 1 REFERENCE 3 REMARK 1 AUTH H.C.WATSON,D.M.SHOTTON,J.M.COX,H.MUIRHEAD REMARK 1 TITL THREE-DIMENSIONAL FOURIER SYNTHESIS OF TOSYL-ELASTASE AT 3.5 REMARK 1 TITL 2 ANGSTROMS RESOLUTION REMARK 1 REF NATURE V. 225 806 1970 REMARK 1 REFN ISSN 0028-0836 REMARK 1 REFERENCE 4 REMARK 1 AUTH D.M.SHOTTON,H.C.WATSON REMARK 1 TITL THREE DIMENSIONAL STRUCTURE OF TOSYL-ELASTASE REMARK 1 REF NATURE V. 225 811 1970 REMARK 1 REFN ISSN 0028-0836 REMARK 1 REFERENCE 5 REMARK 1 EDIT R.J.FELDMANN REMARK 1 REF ATLAS OF MACROMOLECULAR 233 1976 REMARK 1 REF 2 STRUCTURE ON MICROFICHE REMARK 1 PUBL TRACOR JITCO,INC.,ROCKVILLE,MD. REMARK 1 REFN REMARK 1 REFERENCE 6 REMARK 1 EDIT M.O.DAYHOFF REMARK 1 REF ATLAS OF PROTEIN SEQUENCE V. 5 96 1976 REMARK 1 REF 2 AND STRUCTURE,SUPPLEMENT 2 REMARK 1 PUBL NATIONAL BIOMEDICAL RESEARCH FOUNDATION, SILVER SPRING,MD. REMARK 1 REFN ISSN 0-912466-05-7 REMARK 2 REMARK 2 RESOLUTION. 2.50 ANGSTROMS. REMARK 3 REMARK 3 REFINEMENT. REMARK 3 PROGRAM : NULL REMARK 3 AUTHORS : NULL REMARK 3 REMARK 3 DATA USED IN REFINEMENT. REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 2.50 REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : NULL REMARK 3 DATA CUTOFF (SIGMA(F)) : NULL REMARK 3 DATA CUTOFF HIGH (ABS(F)) : NULL REMARK 3 DATA CUTOFF LOW (ABS(F)) : NULL REMARK 3 COMPLETENESS (WORKING+TEST) (%) : NULL REMARK 3 NUMBER OF REFLECTIONS : NULL REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT. REMARK 3 CROSS-VALIDATION METHOD : NULL REMARK 3 FREE R VALUE TEST SET SELECTION : NULL REMARK 3 R VALUE (WORKING SET) : NULL REMARK 3 FREE R VALUE : NULL REMARK 3 FREE R VALUE TEST SET SIZE (%) : NULL REMARK 3 FREE R VALUE TEST SET COUNT : NULL REMARK 3 ESTIMATED ERROR OF FREE R VALUE : NULL REMARK 3 REMARK 3 FIT IN THE HIGHEST RESOLUTION BIN. REMARK 3 TOTAL NUMBER OF BINS USED : NULL REMARK 3 BIN RESOLUTION RANGE HIGH (A) : NULL REMARK 3 BIN RESOLUTION RANGE LOW (A) : NULL REMARK 3 BIN COMPLETENESS (WORKING+TEST) (%) : NULL REMARK 3 REFLECTIONS IN BIN (WORKING SET) : NULL REMARK 3 BIN R VALUE (WORKING SET) : NULL REMARK 3 BIN FREE R VALUE : NULL REMARK 3 BIN FREE R VALUE TEST SET SIZE (%) : NULL REMARK 3 BIN FREE R VALUE TEST SET COUNT : NULL REMARK 3 ESTIMATED ERROR OF BIN FREE R VALUE : NULL REMARK 3 REMARK 3 NUMBER OF NON-HYDROGEN ATOMS USED IN REFINEMENT. REMARK 3 PROTEIN ATOMS : 1822 REMARK 3 NUCLEIC ACID ATOMS : 0 REMARK 3 HETEROGEN ATOMS : 11 REMARK 3 SOLVENT ATOMS : 25 REMARK 3 REMARK 3 B VALUES. REMARK 3 FROM WILSON PLOT (A**2) : NULL REMARK 3 MEAN B VALUE (OVERALL, A**2) : NULL REMARK 3 OVERALL ANISOTROPIC B VALUE. REMARK 3 B11 (A**2) : NULL REMARK 3 B22 (A**2) : NULL REMARK 3 B33 (A**2) : NULL REMARK 3 B12 (A**2) : NULL REMARK 3 B13 (A**2) : NULL REMARK 3 B23 (A**2) : NULL REMARK 3 REMARK 3 ESTIMATED COORDINATE ERROR. REMARK 3 ESD FROM LUZZATI PLOT (A) : NULL REMARK 3 ESD FROM SIGMAA (A) : NULL REMARK 3 LOW RESOLUTION CUTOFF (A) : NULL REMARK 3 REMARK 3 CROSS-VALIDATED ESTIMATED COORDINATE ERROR. REMARK 3 ESD FROM C-V LUZZATI PLOT (A) : NULL REMARK 3 ESD FROM C-V SIGMAA (A) : NULL REMARK 3 REMARK 3 RMS DEVIATIONS FROM IDEAL VALUES. REMARK 3 BOND LENGTHS (A) : NULL REMARK 3 BOND ANGLES (DEGREES) : NULL REMARK 3 DIHEDRAL ANGLES (DEGREES) : NULL REMARK 3 IMPROPER ANGLES (DEGREES) : NULL REMARK 3 REMARK 3 ISOTROPIC THERMAL MODEL : NULL REMARK 3 REMARK 3 ISOTROPIC THERMAL FACTOR RESTRAINTS. RMS SIGMA REMARK 3 MAIN-CHAIN BOND (A**2) : NULL ; NULL REMARK 3 MAIN-CHAIN ANGLE (A**2) : NULL ; NULL REMARK 3 SIDE-CHAIN BOND (A**2) : NULL ; NULL REMARK 3 SIDE-CHAIN ANGLE (A**2) : NULL ; NULL REMARK 3 REMARK 3 NCS MODEL : NULL REMARK 3 REMARK 3 NCS RESTRAINTS. RMS SIGMA/WEIGHT REMARK 3 GROUP 1 POSITIONAL (A) : NULL ; NULL REMARK 3 GROUP 1 B-FACTOR (A**2) : NULL ; NULL REMARK 3 REMARK 3 PARAMETER FILE 1 : NULL REMARK 3 TOPOLOGY FILE 1 : NULL REMARK 3 REMARK 3 OTHER REFINEMENT REMARKS: REMARK 3 COORDINATES FOR THE 27 WATER MOLECULES AND 1 SULPHATE ION REMARK 3 WERE TAKEN FROM THE ARTICLE CITED AS REFERENCE 1. REMARK 4 REMARK 4 1EST COMPLIES WITH FORMAT V. 3.15, 01-DEC-08 REMARK 100 REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY BNL. REMARK 200 REMARK 200 EXPERIMENTAL DETAILS REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION REMARK 200 DATE OF DATA COLLECTION : NULL REMARK 200 TEMPERATURE (KELVIN) : NULL REMARK 200 PH : NULL REMARK 200 NUMBER OF CRYSTALS USED : NULL REMARK 200 REMARK 200 SYNCHROTRON (Y/N) : NULL REMARK 200 RADIATION SOURCE : NULL REMARK 200 BEAMLINE : NULL REMARK 200 X-RAY GENERATOR MODEL : NULL REMARK 200 MONOCHROMATIC OR LAUE (M/L) : NULL REMARK 200 WAVELENGTH OR RANGE (A) : NULL REMARK 200 MONOCHROMATOR : NULL REMARK 200 OPTICS : NULL REMARK 200 REMARK 200 DETECTOR TYPE : NULL REMARK 200 DETECTOR MANUFACTURER : NULL REMARK 200 INTENSITY-INTEGRATION SOFTWARE : NULL REMARK 200 DATA SCALING SOFTWARE : NULL REMARK 200 REMARK 200 NUMBER OF UNIQUE REFLECTIONS : NULL REMARK 200 RESOLUTION RANGE HIGH (A) : NULL REMARK 200 RESOLUTION RANGE LOW (A) : NULL REMARK 200 REJECTION CRITERIA (SIGMA(I)) : NULL REMARK 200 REMARK 200 OVERALL. REMARK 200 COMPLETENESS FOR RANGE (%) : NULL REMARK 200 DATA REDUNDANCY : NULL REMARK 200 R MERGE (I) : NULL REMARK 200 R SYM (I) : NULL REMARK 200 FOR THE DATA SET : NULL REMARK 200 REMARK 200 IN THE HIGHEST RESOLUTION SHELL. REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : NULL REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : NULL REMARK 200 COMPLETENESS FOR SHELL (%) : NULL REMARK 200 DATA REDUNDANCY IN SHELL : NULL REMARK 200 R MERGE FOR SHELL (I) : NULL REMARK 200 R SYM FOR SHELL (I) : NULL REMARK 200 FOR SHELL : NULL REMARK 200 REMARK 200 DIFFRACTION PROTOCOL: NULL REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: NULL REMARK 200 SOFTWARE USED: NULL REMARK 200 STARTING MODEL: NULL REMARK 200 REMARK 200 REMARK: NULL REMARK 280 REMARK 280 CRYSTAL REMARK 280 SOLVENT CONTENT, VS (%): 43.42 REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 2.17 REMARK 280 REMARK 280 CRYSTALLIZATION CONDITIONS: NULL REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 21 21 21 REMARK 290 REMARK 290 SYMOP SYMMETRY REMARK 290 NNNMMM OPERATOR REMARK 290 1555 X,Y,Z REMARK 290 2555 -X+1/2,-Y,Z+1/2 REMARK 290 3555 -X,Y+1/2,-Z+1/2 REMARK 290 4555 X+1/2,-Y+1/2,-Z REMARK 290 REMARK 290 WHERE NNN -> OPERATOR NUMBER REMARK 290 MMM -> TRANSLATION VECTOR REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY REMARK 290 RELATED MOLECULES. REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 2 -1.000000 0.000000 0.000000 25.75000 REMARK 290 SMTRY2 2 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY3 2 0.000000 0.000000 1.000000 37.75000 REMARK 290 SMTRY1 3 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 3 0.000000 1.000000 0.000000 29.00000 REMARK 290 SMTRY3 3 0.000000 0.000000 -1.000000 37.75000 REMARK 290 SMTRY1 4 1.000000 0.000000 0.000000 25.75000 REMARK 290 SMTRY2 4 0.000000 -1.000000 0.000000 29.00000 REMARK 290 SMTRY3 4 0.000000 0.000000 -1.000000 0.00000 REMARK 290 REMARK 290 REMARK: NULL REMARK 300 REMARK 300 BIOMOLECULE: 1 REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON REMARK 300 BURIED SURFACE AREA. REMARK 350 REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN. REMARK 350 REMARK 350 BIOMOLECULE: 1 REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: MONOMERIC REMARK 350 APPLY THE FOLLOWING TO CHAINS: A REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: CLOSE CONTACTS IN SAME ASYMMETRIC UNIT REMARK 500 REMARK 500 THE FOLLOWING ATOMS ARE IN CLOSE CONTACT. REMARK 500 REMARK 500 ATM1 RES C SSEQI ATM2 RES C SSEQI DISTANCE REMARK 500 OG SER A 195 S TSU A 247 1.45 REMARK 500 O GLN A 75 O HOH A 272 1.92 REMARK 500 OD1 ASN A 77 O HOH A 272 2.07 REMARK 500 O ASN A 72 O HOH A 272 2.10 REMARK 500 O HOH A 266 O HOH A 267 2.18 REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: COVALENT BOND LENGTHS REMARK 500 REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT: (10X,I3,1X,2(A3,1X,A1,I4,A1,1X,A4,3X),1X,F6.3) REMARK 500 REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999 REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996 REMARK 500 REMARK 500 M RES CSSEQI ATM1 RES CSSEQI ATM2 DEVIATION REMARK 500 TRP A 27 NE1 TRP A 27 CE2 -0.096 REMARK 500 TRP A 38 NE1 TRP A 38 CE2 -0.096 REMARK 500 TRP A 51 NE1 TRP A 51 CE2 -0.096 REMARK 500 TRP A 94 NE1 TRP A 94 CE2 -0.096 REMARK 500 TRP A 141 NE1 TRP A 141 CE2 -0.095 REMARK 500 TRP A 172 NE1 TRP A 172 CE2 -0.097 REMARK 500 TRP A 237 NE1 TRP A 237 CE2 -0.096 REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: TORSION ANGLES REMARK 500 REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS: REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2) REMARK 500 REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI- REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400 REMARK 500 REMARK 500 M RES CSSEQI PSI PHI REMARK 500 ARG A 24 -47.16 -25.92 REMARK 500 GLU A 62 79.88 -59.54 REMARK 500 HIS A 71 -53.19 -139.06 REMARK 500 ASN A 76 105.70 -59.25 REMARK 500 PRO A 92 -18.69 -43.13 REMARK 500 THR A 96 -39.57 -36.52 REMARK 500 TYR A 101 24.49 48.03 REMARK 500 ASN A 115 -159.95 -139.22 REMARK 500 ASN A 133 8.79 85.71 REMARK 500 ASP A 164 171.31 -58.49 REMARK 500 TYR A 171 -112.76 -109.43 REMARK 500 GLN A 192 107.73 -42.07 REMARK 500 SER A 195 139.16 -38.08 REMARK 500 THR A 213 107.51 -38.46 REMARK 500 SER A 214 -70.91 -98.61 REMARK 500 LYS A 224 72.81 -118.26 REMARK 500 ARG A 230 86.08 -59.39 REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: NON-CIS, NON-TRANS REMARK 500 REMARK 500 THE FOLLOWING PEPTIDE BONDS DEVIATE SIGNIFICANTLY FROM BOTH REMARK 500 CIS AND TRANS CONFORMATION. CIS BONDS, IF ANY, ARE LISTED REMARK 500 ON CISPEP RECORDS. TRANS IS DEFINED AS 180 +/- 30 AND REMARK 500 CIS IS DEFINED AS 0 +/- 30 DEGREES. REMARK 500 MODEL OMEGA REMARK 500 GLY A 197 PRO A 198 -147.45 REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: PLANAR GROUPS REMARK 500 REMARK 500 PLANAR GROUPS IN THE FOLLOWING RESIDUES HAVE A TOTAL REMARK 500 RMS DISTANCE OF ALL ATOMS FROM THE BEST-FIT PLANE REMARK 500 BY MORE THAN AN EXPECTED VALUE OF 6*RMSD, WITH AN REMARK 500 RMSD 0.02 ANGSTROMS, OR AT LEAST ONE ATOM HAS REMARK 500 AN RMSD GREATER THAN THIS VALUE REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 M RES CSSEQI RMS TYPE REMARK 500 TYR A 35 0.12 SIDE CHAIN REMARK 500 ASN A 77 0.08 SIDE CHAIN REMARK 500 TYR A 82 0.07 SIDE CHAIN REMARK 500 TYR A 93 0.12 SIDE CHAIN REMARK 500 ASN A 115 0.07 SIDE CHAIN REMARK 500 TYR A 117 0.07 SIDE CHAIN REMARK 500 TYR A 171 0.07 SIDE CHAIN REMARK 500 ASN A 245 0.08 SIDE CHAIN REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: MAIN CHAIN PLANARITY REMARK 500 REMARK 500 THE FOLLOWING RESIDUES HAVE A PSEUDO PLANARITY REMARK 500 TORSION ANGLE, C(I) - CA(I) - N(I+1) - O(I), GREATER REMARK 500 10.0 DEGREES. (M=MODEL NUMBER; RES=RESIDUE NAME; REMARK 500 C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER; REMARK 500 I=INSERTION CODE). REMARK 500 REMARK 500 M RES CSSEQI ANGLE REMARK 500 GLU A 21 11.54 REMARK 500 GLN A 23 14.85 REMARK 500 LEU A 33 12.94 REMARK 500 ARG A 36 12.22 REMARK 500 SER A 36A 12.84 REMARK 500 HIS A 40 11.42 REMARK 500 CYS A 42 -11.23 REMARK 500 LEU A 46 10.16 REMARK 500 GLN A 49 -10.69 REMARK 500 THR A 54 10.93 REMARK 500 HIS A 57 -14.21 REMARK 500 ARG A 61 12.34 REMARK 500 THR A 64 10.42 REMARK 500 ARG A 65A 10.76 REMARK 500 VAL A 66 12.74 REMARK 500 VAL A 68 10.15 REMARK 500 GLY A 69 11.41 REMARK 500 ASN A 72 12.10 REMARK 500 GLU A 80 11.93 REMARK 500 VAL A 90 12.92 REMARK 500 HIS A 91 10.46 REMARK 500 TRP A 94 15.11 REMARK 500 ASN A 95 12.12 REMARK 500 VAL A 99 -12.42 REMARK 500 ALA A 99A -10.44 REMARK 500 GLY A 100 -10.13 REMARK 500 ILE A 103 11.90 REMARK 500 ARG A 107 13.15 REMARK 500 THR A 113 10.88 REMARK 500 LEU A 114 12.06 REMARK 500 SER A 116 -10.09 REMARK 500 VAL A 118 11.28 REMARK 500 GLY A 121 11.63 REMARK 500 VAL A 122 11.85 REMARK 500 ARG A 125 12.80 REMARK 500 ALA A 126 11.24 REMARK 500 ASN A 132 12.19 REMARK 500 ILE A 138 13.39 REMARK 500 TRP A 141 -10.08 REMARK 500 THR A 147 11.77 REMARK 500 ALA A 152 12.17 REMARK 500 LEU A 155 13.06 REMARK 500 TYR A 159 12.42 REMARK 500 VAL A 163 10.50 REMARK 500 ASP A 164 -11.62 REMARK 500 TYR A 165 -13.20 REMARK 500 ALA A 166 -15.64 REMARK 500 ILE A 167 -11.58 REMARK 500 CYS A 168 -11.77 REMARK 500 SER A 170 11.55 REMARK 500 REMARK 500 THIS ENTRY HAS 78 MAIN CHAIN PLANARITY DEVIATIONS. REMARK 500 REMARK 500 REMARK: NULL REMARK 610 REMARK 610 MISSING HETEROATOM REMARK 610 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER; REMARK 610 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER; REMARK 610 I=INSERTION CODE): REMARK 610 M RES C SSEQI REMARK 610 SO4 A 246 REMARK 610 TSU A 247 REMARK 700 REMARK 700 SHEET REMARK 700 THE TWO SEVEN STRANDED SHEETS IN THIS STRUCTURE ARE REALLY REMARK 700 SIX STRANDED BETA BARRELS - THIS IS DENOTED BY THE FIRST REMARK 700 STRAND RECURRING AS THE LAST STRAND. REMARK 800 REMARK 800 SITE REMARK 800 SITE_IDENTIFIER: CAT REMARK 800 EVIDENCE_CODE: UNKNOWN REMARK 800 SITE_DESCRIPTION: NULL REMARK 800 REMARK 800 SITE_IDENTIFIER: AC1 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SO4 A 246 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC2 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE TOS A 247 DBREF 1EST A 16 245 UNP P00772 ELA1_PIG 27 266 SEQADV 1EST ASN A 77 UNP P00772 ASP 92 CONFLICT SEQRES 1 A 240 VAL VAL GLY GLY THR GLU ALA GLN ARG ASN SER TRP PRO SEQRES 2 A 240 SER GLN ILE SER LEU GLN TYR ARG SER GLY SER SER TRP SEQRES 3 A 240 ALA HIS THR CYS GLY GLY THR LEU ILE ARG GLN ASN TRP SEQRES 4 A 240 VAL MET THR ALA ALA HIS CYS VAL ASP ARG GLU LEU THR SEQRES 5 A 240 PHE ARG VAL VAL VAL GLY GLU HIS ASN LEU ASN GLN ASN SEQRES 6 A 240 ASN GLY THR GLU GLN TYR VAL GLY VAL GLN LYS ILE VAL SEQRES 7 A 240 VAL HIS PRO TYR TRP ASN THR ASP ASP VAL ALA ALA GLY SEQRES 8 A 240 TYR ASP ILE ALA LEU LEU ARG LEU ALA GLN SER VAL THR SEQRES 9 A 240 LEU ASN SER TYR VAL GLN LEU GLY VAL LEU PRO ARG ALA SEQRES 10 A 240 GLY THR ILE LEU ALA ASN ASN SER PRO CYS TYR ILE THR SEQRES 11 A 240 GLY TRP GLY LEU THR ARG THR ASN GLY GLN LEU ALA GLN SEQRES 12 A 240 THR LEU GLN GLN ALA TYR LEU PRO THR VAL ASP TYR ALA SEQRES 13 A 240 ILE CYS SER SER SER SER TYR TRP GLY SER THR VAL LYS SEQRES 14 A 240 ASN SER MET VAL CYS ALA GLY GLY ASP GLY VAL ARG SER SEQRES 15 A 240 GLY CYS GLN GLY ASP SER GLY GLY PRO LEU HIS CYS LEU SEQRES 16 A 240 VAL ASN GLY GLN TYR ALA VAL HIS GLY VAL THR SER PHE SEQRES 17 A 240 VAL SER ARG LEU GLY CYS ASN VAL THR ARG LYS PRO THR SEQRES 18 A 240 VAL PHE THR ARG VAL SER ALA TYR ILE SER TRP ILE ASN SEQRES 19 A 240 ASN VAL ILE ALA SER ASN HET SO4 A 246 1 HET TSU A 247 10 HETNAM SO4 SULFATE ION HETNAM TSU PARA-TOLUENE SULFONATE FORMUL 2 SO4 O4 S 2- FORMUL 3 TSU C7 H8 O3 S FORMUL 4 HOH *25(H2 O) HELIX 1 HA ASP A 164 SER A 170 1 7 HELIX 2 HB TYR A 234 ASN A 245 1HELICAL TAIL AT CARBOXY END 12 SHEET 1 A 7 SER A 29 SER A 36A 0 SHEET 2 A 7 SER A 37 ILE A 47 -1 SHEET 3 A 7 ASN A 50 ALA A 56 -1 SHEET 4 A 7 ASP A 102 GLN A 110 -1 SHEET 5 A 7 GLU A 80 HIS A 91 -1 SHEET 6 A 7 PHE A 65 GLY A 69 -1 SHEET 7 A 7 SER A 29 SER A 36A-1 SHEET 1 B 7 ASN A 133 THR A 144 0 SHEET 2 B 7 GLY A 149 VAL A 163 -1 SHEET 3 B 7 SER A 179 VAL A 188 -1 SHEET 4 B 7 ASN A 221 VAL A 231 -1 SHEET 5 B 7 HIS A 210 VAL A 216 -1 SHEET 6 B 7 SER A 195 CYS A 201 -1 SHEET 7 B 7 ASN A 133 THR A 144 -1 SHEET 1 C 3 GLY A 149 ALA A 152 0 SHEET 2 C 3 TRP A 141 LEU A 143 -1 SHEET 3 C 3 GLN A 192 ASP A 194 -1 SSBOND 1 CYS A 42 CYS A 58 1555 1555 2.03 SSBOND 2 CYS A 136 CYS A 201 1555 1555 2.04 SSBOND 3 CYS A 168 CYS A 182 1555 1555 2.03 SSBOND 4 CYS A 191 CYS A 220 1555 1555 2.03 SITE 1 CAT 3 HIS A 57 ASP A 102 SER A 195 SITE 1 AC1 1 ARG A 230 SITE 1 AC2 5 CYS A 191 GLN A 192 GLY A 193 SER A 195 SITE 2 AC2 5 SER A 214 CRYST1 51.500 58.000 75.500 90.00 90.00 90.00 P 21 21 21 4 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 0.019417 0.000000 0.000000 0.00000 SCALE2 0.000000 0.017241 0.000000 0.00000 SCALE3 0.000000 0.000000 0.013245 0.00000 ATOM 1 N VAL A 16 -10.259 32.951 35.052 1.00 0.00 N ATOM 2 CA VAL A 16 -11.137 33.755 35.924 1.00 0.00 C ATOM 3 C VAL A 16 -12.287 34.427 35.174 1.00 0.00 C ATOM 4 O VAL A 16 -12.049 35.172 34.215 1.00 0.00 O ATOM 5 CB VAL A 16 -10.330 34.815 36.679 1.00 0.00 C ATOM 6 CG1 VAL A 16 -11.217 35.815 37.418 1.00 0.00 C ATOM 7 CG2 VAL A 16 -9.287 34.204 37.610 1.00 0.00 C ATOM 8 N VAL A 17 -13.481 33.908 35.414 1.00 0.00 N ATOM 9 CA VAL A 17 -14.699 34.440 34.794 1.00 0.00 C ATOM 10 C VAL A 17 -15.260 35.626 35.578 1.00 0.00 C ATOM 11 O VAL A 17 -15.222 35.610 36.815 1.00 0.00 O ATOM 12 CB VAL A 17 -15.762 33.344 34.723 1.00 0.00 C ATOM 13 CG1 VAL A 17 -17.005 33.814 33.973 1.00 0.00 C ATOM 14 CG2 VAL A 17 -15.212 32.055 34.119 1.00 0.00 C ATOM 15 N GLY A 18 -15.443 36.724 34.861 1.00 0.00 N ATOM 16 CA GLY A 18 -16.037 37.948 35.413 1.00 0.00 C ATOM 17 C GLY A 18 -15.026 38.773 36.201 1.00 0.00 C ATOM 18 O GLY A 18 -15.376 39.402 37.208 1.00 0.00 O ATOM 19 N GLY A 19 -13.769 38.571 35.852 1.00 0.00 N ATOM 20 CA GLY A 19 -12.655 39.253 36.520 1.00 0.00 C ATOM 21 C GLY A 19 -12.114 40.455 35.749 1.00 0.00 C ATOM 22 O GLY A 19 -12.694 40.856 34.732 1.00 0.00 O ATOM 23 N THR A 20 -11.258 41.186 36.443 1.00 0.00 N ATOM 24 CA THR A 20 -10.574 42.377 35.920 1.00 0.00 C ATOM 25 C THR A 20 -9.071 42.141 35.834 1.00 0.00 C ATOM 26 O THR A 20 -8.543 41.280 36.544 1.00 0.00 O ATOM 27 CB THR A 20 -10.786 43.548 36.874 1.00 0.00 C ATOM 28 OG1 THR A 20 -10.138 43.250 38.107 1.00 0.00 O ATOM 29 CG2 THR A 20 -12.263 43.850 37.119 1.00 0.00 C ATOM 30 N GLU A 21 -8.392 43.011 35.118 1.00 0.00 N ATOM 31 CA GLU A 21 -6.935 42.915 35.001 1.00 0.00 C ATOM 32 C GLU A 21 -6.232 43.483 36.230 1.00 0.00 C ATOM 33 O GLU A 21 -6.739 44.437 36.834 1.00 0.00 O ATOM 34 CB GLU A 21 -6.452 43.624 33.735 1.00 0.00 C ATOM 35 CG GLU A 21 -4.946 43.473 33.523 1.00 0.00 C ATOM 36 CD GLU A 21 -4.544 44.110 32.197 1.00 0.00 C ATOM 37 OE1 GLU A 21 -3.364 44.438 32.021 1.00 0.00 O ATOM 38 OE2 GLU A 21 -5.359 44.116 31.265 1.00 0.00 O ATOM 39 N ALA A 22 -5.390 42.636 36.799 1.00 0.00 N ATOM 40 CA ALA A 22 -4.582 42.981 37.976 1.00 0.00 C ATOM 41 C ALA A 22 -3.391 43.878 37.645 1.00 0.00 C ATOM 42 O ALA A 22 -3.167 44.215 36.476 1.00 0.00 O ATOM 43 CB ALA A 22 -4.068 41.701 38.631 1.00 0.00 C ATOM 44 N GLN A 23 -2.879 44.510 38.687 1.00 0.00 N ATOM 45 CA GLN A 23 -1.679 45.347 38.576 1.00 0.00 C ATOM 46 C GLN A 23 -0.441 44.522 38.914 1.00 0.00 C ATOM 47 O GLN A 23 -0.596 43.516 39.619 1.00 0.00 O ATOM 48 CB GLN A 23 -1.783 46.525 39.539 1.00 0.00 C ATOM 49 CG GLN A 23 -3.090 47.296 39.372 1.00 0.00 C ATOM 50 CD GLN A 23 -3.235 48.278 40.530 1.00 0.00 C ATOM 51 OE1 GLN A 23 -2.506 48.158 41.523 1.00 0.00 O ATOM 52 NE2 GLN A 23 -4.377 48.949 40.540 1.00 0.00 N ATOM 53 N ARG A 24 0.505 44.620 37.993 1.00 0.00 N ATOM 54 CA ARG A 24 1.801 43.917 38.007 1.00 0.00 C ATOM 55 C ARG A 24 2.325 43.520 39.384 1.00 0.00 C ATOM 56 O ARG A 24 2.640 42.348 39.625 1.00 0.00 O ATOM 57 CB ARG A 24 2.871 44.754 37.315 1.00 0.00 C ATOM 58 CG ARG A 24 2.542 45.005 35.849 1.00 0.00 C ATOM 59 CD ARG A 24 3.725 45.613 35.101 1.00 0.00 C ATOM 60 NE ARG A 24 3.387 45.759 33.679 1.00 0.00 N ATOM 61 CZ ARG A 24 3.728 44.873 32.754 1.00 0.00 C ATOM 62 NH1 ARG A 24 3.381 45.074 31.493 1.00 0.00 N ATOM 63 NH2 ARG A 24 4.480 43.829 33.071 1.00 0.00 N ATOM 64 N ASN A 25 2.272 44.472 40.288 1.00 0.00 N ATOM 65 CA ASN A 25 2.844 44.312 41.628 1.00 0.00 C ATOM 66 C ASN A 25 1.838 43.861 42.681 1.00 0.00 C ATOM 67 O ASN A 25 2.178 43.817 43.870 1.00 0.00 O ATOM 68 CB ASN A 25 3.524 45.606 42.077 1.00 0.00 C ATOM 69 CG ASN A 25 2.528 46.763 42.179 1.00 0.00 C ATOM 70 OD1 ASN A 25 1.429 46.720 41.609 1.00 0.00 O ATOM 71 ND2 ASN A 25 3.067 47.887 42.623 1.00 0.00 N ATOM 72 N SER A 26 0.582 43.847 42.266 1.00 0.00 N ATOM 73 CA SER A 26 -0.518 43.480 43.173 1.00 0.00 C ATOM 74 C SER A 26 -0.368 42.129 43.863 1.00 0.00 C ATOM 75 O SER A 26 -0.370 42.071 45.099 1.00 0.00 O ATOM 76 CB SER A 26 -1.882 43.549 42.494 1.00 0.00 C ATOM 77 OG SER A 26 -2.162 44.895 42.138 1.00 0.00 O ATOM 78 N TRP A 27 -0.248 41.075 43.071 1.00 0.00 N ATOM 79 CA TRP A 27 -0.233 39.708 43.628 1.00 0.00 C ATOM 80 C TRP A 27 1.037 38.911 43.317 1.00 0.00 C ATOM 81 O TRP A 27 0.990 37.980 42.504 1.00 0.00 O ATOM 82 CB TRP A 27 -1.440 38.922 43.101 1.00 0.00 C ATOM 83 CG TRP A 27 -2.766 39.699 43.206 1.00 0.00 C ATOM 84 CD1 TRP A 27 -3.503 40.259 42.222 1.00 0.00 C ATOM 85 CD2 TRP A 27 -3.466 39.982 44.381 1.00 0.00 C ATOM 86 NE1 TRP A 27 -4.637 40.852 42.742 1.00 0.00 N ATOM 87 CE2 TRP A 27 -4.636 40.690 44.007 1.00 0.00 C ATOM 88 CE3 TRP A 27 -3.197 39.675 45.706 1.00 0.00 C ATOM 89 CZ2 TRP A 27 -5.610 41.078 44.912 1.00 0.00 C ATOM 90 CZ3 TRP A 27 -4.164 40.093 46.631 1.00 0.00 C ATOM 91 CH2 TRP A 27 -5.333 40.764 46.248 1.00 0.00 C ATOM 92 N PRO A 28 2.105 39.137 44.072 1.00 0.00 N ATOM 93 CA PRO A 28 3.462 38.827 43.585 1.00 0.00 C ATOM 94 C PRO A 28 3.951 37.452 44.037 1.00 0.00 C ATOM 95 O PRO A 28 5.091 37.072 43.744 1.00 0.00 O ATOM 96 CB PRO A 28 4.352 39.918 44.167 1.00 0.00 C ATOM 97 CG PRO A 28 3.678 40.282 45.474 1.00 0.00 C ATOM 98 CD PRO A 28 2.191 40.100 45.194 1.00 0.00 C ATOM 99 N SER A 29 3.007 36.647 44.490 1.00 0.00 N ATOM 100 CA SER A 29 3.290 35.270 44.914 1.00 0.00 C ATOM 101 C SER A 29 2.720 34.280 43.905 1.00 0.00 C ATOM 102 O SER A 29 2.803 33.062 44.106 1.00 0.00 O ATOM 103 CB SER A 29 2.677 35.000 46.283 1.00 0.00 C ATOM 104 OG SER A 29 1.261 35.078 46.174 1.00 0.00 O ATOM 105 N GLN A 30 1.878 34.847 43.056 1.00 0.00 N ATOM 106 CA GLN A 30 1.218 34.136 41.952 1.00 0.00 C ATOM 107 C GLN A 30 2.220 33.621 40.921 1.00 0.00 C ATOM 108 O GLN A 30 3.148 34.352 40.554 1.00 0.00 O ATOM 109 CB GLN A 30 0.244 35.098 41.267 1.00 0.00 C ATOM 110 CG GLN A 30 -0.429 34.532 40.014 1.00 0.00 C ATOM 111 CD GLN A 30 -1.427 33.438 40.381 1.00 0.00 C ATOM 112 OE1 GLN A 30 -2.577 33.754 40.712 1.00 0.00 O ATOM 113 NE2 GLN A 30 -1.104 32.238 39.921 1.00 0.00 N ATOM 114 N ILE A 31 2.221 32.305 40.748 1.00 0.00 N ATOM 115 CA ILE A 31 3.075 31.681 39.725 1.00 0.00 C ATOM 116 C ILE A 31 2.292 30.995 38.608 1.00 0.00 C ATOM 117 O ILE A 31 1.109 30.671 38.776 1.00 0.00 O ATOM 118 CB ILE A 31 4.122 30.740 40.341 1.00 0.00 C ATOM 119 CG1 ILE A 31 3.571 29.438 40.928 1.00 0.00 C ATOM 120 CG2 ILE A 31 4.985 31.461 41.370 1.00 0.00 C ATOM 121 CD1 ILE A 31 3.559 28.258 39.953 1.00 0.00 C ATOM 122 N SER A 32 2.969 30.831 37.482 1.00 0.00 N ATOM 123 CA SER A 32 2.433 30.097 36.330 1.00 0.00 C ATOM 124 C SER A 32 3.102 28.739 36.138 1.00 0.00 C ATOM 125 O SER A 32 4.335 28.663 36.069 1.00 0.00 O ATOM 126 CB SER A 32 2.597 30.905 35.049 1.00 0.00 C ATOM 127 OG SER A 32 2.185 30.090 33.955 1.00 0.00 O ATOM 128 N LEU A 33 2.315 27.710 36.387 1.00 0.00 N ATOM 129 CA LEU A 33 2.749 26.318 36.213 1.00 0.00 C ATOM 130 C LEU A 33 2.512 25.861 34.778 1.00 0.00 C ATOM 131 O LEU A 33 1.385 25.991 34.280 1.00 0.00 O ATOM 132 CB LEU A 33 1.993 25.403 37.177 1.00 0.00 C ATOM 133 CG LEU A 33 2.471 23.953 37.115 1.00 0.00 C ATOM 134 CD1 LEU A 33 3.951 23.827 37.474 1.00 0.00 C ATOM 135 CD2 LEU A 33 1.605 23.034 37.974 1.00 0.00 C ATOM 136 N GLN A 34 3.622 25.845 34.056 1.00 0.00 N ATOM 137 CA GLN A 34 3.644 25.487 32.634 1.00 0.00 C ATOM 138 C GLN A 34 4.269 24.125 32.346 1.00 0.00 C ATOM 139 O GLN A 34 5.120 23.668 33.115 1.00 0.00 O ATOM 140 CB GLN A 34 4.409 26.561 31.866 1.00 0.00 C ATOM 141 CG GLN A 34 3.772 27.932 32.068 1.00 0.00 C ATOM 142 CD GLN A 34 4.553 28.999 31.308 1.00 0.00 C ATOM 143 OE1 GLN A 34 5.676 28.747 30.855 1.00 0.00 O ATOM 144 NE2 GLN A 34 4.030 30.214 31.373 1.00 0.00 N ATOM 145 N TYR A 35 3.686 23.426 31.378 1.00 0.00 N ATOM 146 CA TYR A 35 4.229 22.144 30.897 1.00 0.00 C ATOM 147 C TYR A 35 4.737 22.223 29.458 1.00 0.00 C ATOM 148 O TYR A 35 4.328 23.120 28.709 1.00 0.00 O ATOM 149 CB TYR A 35 3.283 20.951 31.104 1.00 0.00 C ATOM 150 CG TYR A 35 2.055 20.947 30.176 1.00 0.00 C ATOM 151 CD1 TYR A 35 0.923 21.666 30.518 1.00 0.00 C ATOM 152 CD2 TYR A 35 2.058 20.178 29.022 1.00 0.00 C ATOM 153 CE1 TYR A 35 -0.198 21.663 29.679 1.00 0.00 C ATOM 154 CE2 TYR A 35 0.942 20.168 28.177 1.00 0.00 C ATOM 155 CZ TYR A 35 -0.187 20.917 28.503 1.00 0.00 C ATOM 156 OH TYR A 35 -1.064 21.265 27.496 1.00 0.00 O ATOM 157 N ARG A 36 5.835 21.527 29.216 1.00 0.00 N ATOM 158 CA ARG A 36 6.459 21.579 27.889 1.00 0.00 C ATOM 159 C ARG A 36 5.694 20.809 26.819 1.00 0.00 C ATOM 160 O ARG A 36 5.580 19.580 26.904 1.00 0.00 O ATOM 161 CB ARG A 36 7.934 21.187 27.899 1.00 0.00 C ATOM 162 CG ARG A 36 8.508 21.235 26.483 1.00 0.00 C ATOM 163 CD ARG A 36 10.011 20.975 26.431 1.00 0.00 C ATOM 164 NE ARG A 36 10.720 22.210 26.064 1.00 0.00 N ATOM 165 CZ ARG A 36 11.865 22.583 26.617 1.00 0.00 C ATOM 166 NH1 ARG A 36 12.449 23.705 26.225 1.00 0.00 N ATOM 167 NH2 ARG A 36 12.546 21.719 27.355 1.00 0.00 N ATOM 168 N SER A 36A 4.832 21.573 26.178 1.00 0.00 N ATOM 169 CA SER A 36A 4.005 21.065 25.083 1.00 0.00 C ATOM 170 C SER A 36A 4.752 21.029 23.753 1.00 0.00 C ATOM 171 O SER A 36A 4.766 22.045 23.043 1.00 0.00 O ATOM 172 CB SER A 36A 2.740 21.901 24.940 1.00 0.00 C ATOM 173 OG SER A 36A 1.970 21.372 23.866 1.00 0.00 O ATOM 174 N GLY A 36B 5.703 20.110 23.741 1.00 0.00 N ATOM 175 CA GLY A 36B 6.506 19.772 22.558 1.00 0.00 C ATOM 176 C GLY A 36B 7.607 20.781 22.246 1.00 0.00 C ATOM 177 O GLY A 36B 8.660 20.765 22.895 1.00 0.00 O ATOM 178 N SER A 36C 7.186 21.827 21.563 1.00 0.00 N ATOM 179 CA SER A 36C 8.085 22.881 21.083 1.00 0.00 C ATOM 180 C SER A 36C 8.212 24.020 22.084 1.00 0.00 C ATOM 181 O SER A 36C 9.202 24.761 22.064 1.00 0.00 O ATOM 182 CB SER A 36C 7.527 23.454 19.785 1.00 0.00 C ATOM 183 OG SER A 36C 7.338 22.397 18.852 1.00 0.00 O ATOM 184 N SER A 37 7.072 24.332 22.661 1.00 0.00 N ATOM 185 CA SER A 37 6.960 25.450 23.600 1.00 0.00 C ATOM 186 C SER A 37 6.357 25.036 24.935 1.00 0.00 C ATOM 187 O SER A 37 6.181 23.842 25.200 1.00 0.00 O ATOM 188 CB SER A 37 6.098 26.544 22.983 1.00 0.00 C ATOM 189 OG SER A 37 4.817 25.996 22.698 1.00 0.00 O ATOM 190 N TRP A 38 6.144 26.035 25.768 1.00 0.00 N ATOM 191 CA TRP A 38 5.584 25.859 27.110 1.00 0.00 C ATOM 192 C TRP A 38 4.155 26.389 27.202 1.00 0.00 C ATOM 193 O TRP A 38 3.827 27.413 26.590 1.00 0.00 O ATOM 194 CB TRP A 38 6.456 26.570 28.143 1.00 0.00 C ATOM 195 CG TRP A 38 7.869 25.968 28.240 1.00 0.00 C ATOM 196 CD1 TRP A 38 8.980 26.241 27.521 1.00 0.00 C ATOM 197 CD2 TRP A 38 8.267 24.995 29.156 1.00 0.00 C ATOM 198 NE1 TRP A 38 10.041 25.479 27.966 1.00 0.00 N ATOM 199 CE2 TRP A 38 9.643 24.750 28.933 1.00 0.00 C ATOM 200 CE3 TRP A 38 7.565 24.341 30.153 1.00 0.00 C ATOM 201 CZ2 TRP A 38 10.389 23.870 29.699 1.00 0.00 C ATOM 202 CZ3 TRP A 38 8.310 23.433 30.917 1.00 0.00 C ATOM 203 CH2 TRP A 38 9.675 23.206 30.701 1.00 0.00 C ATOM 204 N ALA A 39 3.310 25.601 27.842 1.00 0.00 N ATOM 205 CA ALA A 39 1.883 25.915 27.986 1.00 0.00 C ATOM 206 C ALA A 39 1.431 26.037 29.439 1.00 0.00 C ATOM 207 O ALA A 39 1.617 25.101 30.225 1.00 0.00 O ATOM 208 CB ALA A 39 1.052 24.836 27.296 1.00 0.00 C ATOM 209 N HIS A 40 0.663 27.083 29.695 1.00 0.00 N ATOM 210 CA HIS A 40 0.070 27.343 31.014 1.00 0.00 C ATOM 211 C HIS A 40 -1.026 26.338 31.351 1.00 0.00 C ATOM 212 O HIS A 40 -1.852 26.031 30.481 1.00 0.00 O ATOM 213 CB HIS A 40 -0.523 28.753 31.040 1.00 0.00 C ATOM 214 CG HIS A 40 -1.312 29.021 32.333 1.00 0.00 C ATOM 215 ND1 HIS A 40 -0.690 29.269 33.523 1.00 0.00 N ATOM 216 CD2 HIS A 40 -2.644 29.042 32.541 1.00 0.00 C ATOM 217 CE1 HIS A 40 -1.659 29.468 34.465 1.00 0.00 C ATOM 218 NE2 HIS A 40 -2.872 29.316 33.860 1.00 0.00 N ATOM 219 N THR A 41 -0.765 25.554 32.380 1.00 0.00 N ATOM 220 CA THR A 41 -1.780 24.597 32.828 1.00 0.00 C ATOM 221 C THR A 41 -2.477 24.979 34.129 1.00 0.00 C ATOM 222 O THR A 41 -3.704 24.861 34.230 1.00 0.00 O ATOM 223 CB THR A 41 -1.264 23.160 32.891 1.00 0.00 C ATOM 224 OG1 THR A 41 -2.327 22.319 33.323 1.00 0.00 O ATOM 225 CG2 THR A 41 -0.062 22.970 33.817 1.00 0.00 C ATOM 226 N CYS A 42 -1.714 25.560 35.036 1.00 0.00 N ATOM 227 CA CYS A 42 -2.213 25.905 36.371 1.00 0.00 C ATOM 228 C CYS A 42 -1.579 27.147 36.984 1.00 0.00 C ATOM 229 O CYS A 42 -0.434 27.481 36.666 1.00 0.00 O ATOM 230 CB CYS A 42 -1.992 24.744 37.338 1.00 0.00 C ATOM 231 SG CYS A 42 -3.165 23.375 37.244 1.00 0.00 S ATOM 232 N GLY A 43 -2.148 27.496 38.122 1.00 0.00 N ATOM 233 CA GLY A 43 -1.626 28.552 38.990 1.00 0.00 C ATOM 234 C GLY A 43 -0.828 27.945 40.142 1.00 0.00 C ATOM 235 O GLY A 43 -0.874 26.725 40.347 1.00 0.00 O ATOM 236 N GLY A 44 -0.319 28.809 41.000 1.00 0.00 N ATOM 237 CA GLY A 44 0.466 28.381 42.164 1.00 0.00 C ATOM 238 C GLY A 44 0.856 29.536 43.082 1.00 0.00 C ATOM 239 O GLY A 44 0.663 30.708 42.735 1.00 0.00 O ATOM 240 N THR A 45 1.441 29.175 44.216 1.00 0.00 N ATOM 241 CA THR A 45 1.868 30.147 45.230 1.00 0.00 C ATOM 242 C THR A 45 3.272 29.901 45.778 1.00 0.00 C ATOM 243 O THR A 45 3.557 28.820 46.307 1.00 0.00 O ATOM 244 CB THR A 45 0.863 30.184 46.377 1.00 0.00 C ATOM 245 OG1 THR A 45 -0.439 30.392 45.844 1.00 0.00 O ATOM 246 CG2 THR A 45 1.179 31.282 47.391 1.00 0.00 C ATOM 247 N LEU A 46 4.162 30.811 45.422 1.00 0.00 N ATOM 248 CA LEU A 46 5.549 30.797 45.901 1.00 0.00 C ATOM 249 C LEU A 46 5.588 30.998 47.415 1.00 0.00 C ATOM 250 O LEU A 46 5.048 32.000 47.896 1.00 0.00 O ATOM 251 CB LEU A 46 6.294 31.962 45.255 1.00 0.00 C ATOM 252 CG LEU A 46 7.803 31.876 45.465 1.00 0.00 C ATOM 253 CD1 LEU A 46 8.410 30.747 44.634 1.00 0.00 C ATOM 254 CD2 LEU A 46 8.481 33.208 45.159 1.00 0.00 C ATOM 255 N ILE A 47 5.853 29.918 48.132 1.00 0.00 N ATOM 256 CA ILE A 47 5.884 29.980 49.604 1.00 0.00 C ATOM 257 C ILE A 47 7.278 30.130 50.213 1.00 0.00 C ATOM 258 O ILE A 47 7.395 30.437 51.406 1.00 0.00 O ATOM 259 CB ILE A 47 5.086 28.843 50.239 1.00 0.00 C ATOM 260 CG1 ILE A 47 5.522 27.463 49.749 1.00 0.00 C ATOM 261 CG2 ILE A 47 3.581 29.055 50.086 1.00 0.00 C ATOM 262 CD1 ILE A 47 4.715 26.345 50.402 1.00 0.00 C ATOM 263 N ARG A 48 8.245 29.565 49.504 1.00 0.00 N ATOM 264 CA ARG A 48 9.684 29.729 49.772 1.00 0.00 C ATOM 265 C ARG A 48 10.369 30.114 48.466 1.00 0.00 C ATOM 266 O ARG A 48 9.801 29.836 47.404 1.00 0.00 O ATOM 267 CB ARG A 48 10.321 28.428 50.263 1.00 0.00 C ATOM 268 CG ARG A 48 9.802 27.922 51.607 1.00 0.00 C ATOM 269 CD ARG A 48 10.103 28.882 52.757 1.00 0.00 C ATOM 270 NE ARG A 48 9.819 28.218 54.037 1.00 0.00 N ATOM 271 CZ ARG A 48 8.760 28.468 54.792 1.00 0.00 C ATOM 272 NH1 ARG A 48 8.605 27.809 55.931 1.00 0.00 N ATOM 273 NH2 ARG A 48 7.772 29.218 54.322 1.00 0.00 N ATOM 274 N GLN A 49 11.611 30.578 48.547 1.00 0.00 N ATOM 275 CA GLN A 49 12.365 30.987 47.350 1.00 0.00 C ATOM 276 C GLN A 49 12.631 29.823 46.398 1.00 0.00 C ATOM 277 O GLN A 49 12.638 30.013 45.176 1.00 0.00 O ATOM 278 CB GLN A 49 13.691 31.647 47.726 1.00 0.00 C ATOM 279 CG GLN A 49 13.499 32.938 48.520 1.00 0.00 C ATOM 280 CD GLN A 49 14.855 33.611 48.721 1.00 0.00 C ATOM 281 OE1 GLN A 49 15.312 33.778 49.860 1.00 0.00 O ATOM 282 NE2 GLN A 49 15.418 34.079 47.616 1.00 0.00 N ATOM 283 N ASN A 50 12.420 28.640 46.944 1.00 0.00 N ATOM 284 CA ASN A 50 12.629 27.375 46.232 1.00 0.00 C ATOM 285 C ASN A 50 11.456 26.402 46.344 1.00 0.00 C ATOM 286 O ASN A 50 11.592 25.237 45.953 1.00 0.00 O ATOM 287 CB ASN A 50 13.905 26.695 46.721 1.00 0.00 C ATOM 288 CG ASN A 50 13.769 26.312 48.193 1.00 0.00 C ATOM 289 OD1 ASN A 50 13.465 27.170 49.034 1.00 0.00 O ATOM 290 ND2 ASN A 50 14.375 25.177 48.498 1.00 0.00 N ATOM 291 N TRP A 51 10.436 26.813 47.088 1.00 0.00 N ATOM 292 CA TRP A 51 9.199 26.016 47.253 1.00 0.00 C ATOM 293 C TRP A 51 7.936 26.686 46.709 1.00 0.00 C ATOM 294 O TRP A 51 7.648 27.844 47.040 1.00 0.00 O ATOM 295 CB TRP A 51 8.960 25.583 48.703 1.00 0.00 C ATOM 296 CG TRP A 51 9.879 24.433 49.149 1.00 0.00 C ATOM 297 CD1 TRP A 51 11.074 24.475 49.772 1.00 0.00 C ATOM 298 CD2 TRP A 51 9.594 23.074 49.014 1.00 0.00 C ATOM 299 NE1 TRP A 51 11.557 23.200 49.979 1.00 0.00 N ATOM 300 CE2 TRP A 51 10.701 22.365 49.538 1.00 0.00 C ATOM 301 CE3 TRP A 51 8.498 22.417 48.476 1.00 0.00 C ATOM 302 CZ2 TRP A 51 10.781 20.983 49.541 1.00 0.00 C ATOM 303 CZ3 TRP A 51 8.571 21.016 48.483 1.00 0.00 C ATOM 304 CH2 TRP A 51 9.674 20.322 48.995 1.00 0.00 C ATOM 305 N VAL A 52 7.137 25.876 46.015 1.00 0.00 N ATOM 306 CA VAL A 52 5.857 26.278 45.395 1.00 0.00 C ATOM 307 C VAL A 52 4.675 25.395 45.803 1.00 0.00 C ATOM 308 O VAL A 52 4.812 24.170 45.878 1.00 0.00 O ATOM 309 CB VAL A 52 6.000 26.298 43.868 1.00 0.00 C ATOM 310 CG1 VAL A 52 4.667 26.308 43.120 1.00 0.00 C ATOM 311 CG2 VAL A 52 6.930 27.406 43.381 1.00 0.00 C ATOM 312 N MET A 53 3.606 26.038 46.253 1.00 0.00 N ATOM 313 CA MET A 53 2.364 25.360 46.656 1.00 0.00 C ATOM 314 C MET A 53 1.282 25.419 45.580 1.00 0.00 C ATOM 315 O MET A 53 0.953 26.510 45.099 1.00 0.00 O ATOM 316 CB MET A 53 1.824 25.993 47.937 1.00 0.00 C ATOM 317 CG MET A 53 0.512 25.356 48.394 1.00 0.00 C ATOM 318 SD MET A 53 -0.233 26.098 49.862 1.00 0.00 S ATOM 319 CE MET A 53 -0.384 27.799 49.273 1.00 0.00 C ATOM 320 N THR A 54 0.999 24.256 45.011 1.00 0.00 N ATOM 321 CA THR A 54 -0.053 24.100 43.993 1.00 0.00 C ATOM 322 C THR A 54 -0.996 22.939 44.316 1.00 0.00 C ATOM 323 O THR A 54 -1.095 22.558 45.488 1.00 0.00 O ATOM 324 CB THR A 54 0.591 23.923 42.616 1.00 0.00 C ATOM 325 OG1 THR A 54 -0.379 24.040 41.576 1.00 0.00 O ATOM 326 CG2 THR A 54 1.383 22.621 42.484 1.00 0.00 C ATOM 327 N ALA A 55 -1.932 22.704 43.411 1.00 0.00 N ATOM 328 CA ALA A 55 -2.895 21.605 43.523 1.00 0.00 C ATOM 329 C ALA A 55 -2.368 20.325 42.885 1.00 0.00 C ATOM 330 O ALA A 55 -1.592 20.383 41.923 1.00 0.00 O ATOM 331 CB ALA A 55 -4.220 21.982 42.866 1.00 0.00 C ATOM 332 N ALA A 56 -2.527 19.258 43.644 1.00 0.00 N ATOM 333 CA ALA A 56 -2.079 17.918 43.248 1.00 0.00 C ATOM 334 C ALA A 56 -2.672 17.458 41.918 1.00 0.00 C ATOM 335 O ALA A 56 -1.958 16.873 41.092 1.00 0.00 O ATOM 336 CB ALA A 56 -2.464 16.931 44.341 1.00 0.00 C ATOM 337 N HIS A 57 -3.817 18.052 41.621 1.00 0.00 N ATOM 338 CA HIS A 57 -4.612 17.733 40.431 1.00 0.00 C ATOM 339 C HIS A 57 -3.922 18.195 39.152 1.00 0.00 C ATOM 340 O HIS A 57 -3.791 17.397 38.213 1.00 0.00 O ATOM 341 CB HIS A 57 -5.980 18.402 40.537 1.00 0.00 C ATOM 342 CG HIS A 57 -6.992 17.713 39.612 1.00 0.00 C ATOM 343 ND1 HIS A 57 -6.617 16.713 38.757 1.00 0.00 N ATOM 344 CD2 HIS A 57 -8.316 17.907 39.490 1.00 0.00 C ATOM 345 CE1 HIS A 57 -7.736 16.298 38.086 1.00 0.00 C ATOM 346 NE2 HIS A 57 -8.788 17.043 38.541 1.00 0.00 N ATOM 347 N CYS A 58 -3.067 19.174 39.379 1.00 0.00 N ATOM 348 CA CYS A 58 -2.285 19.808 38.311 1.00 0.00 C ATOM 349 C CYS A 58 -1.098 18.962 37.877 1.00 0.00 C ATOM 350 O CYS A 58 -0.610 19.104 36.750 1.00 0.00 O ATOM 351 CB CYS A 58 -1.757 21.151 38.800 1.00 0.00 C ATOM 352 SG CYS A 58 -3.009 22.423 39.034 1.00 0.00 S ATOM 353 N VAL A 59 -0.529 18.285 38.852 1.00 0.00 N ATOM 354 CA VAL A 59 0.687 17.507 38.607 1.00 0.00 C ATOM 355 C VAL A 59 0.453 16.002 38.518 1.00 0.00 C ATOM 356 O VAL A 59 1.346 15.214 38.854 1.00 0.00 O ATOM 357 CB VAL A 59 1.770 17.856 39.629 1.00 0.00 C ATOM 358 CG1 VAL A 59 2.402 19.220 39.356 1.00 0.00 C ATOM 359 CG2 VAL A 59 1.278 17.736 41.070 1.00 0.00 C ATOM 360 N ASP A 60 -0.785 15.642 38.195 1.00 0.00 N ATOM 361 CA ASP A 60 -1.157 14.230 37.993 1.00 0.00 C ATOM 362 C ASP A 60 -0.395 13.541 36.865 1.00 0.00 C ATOM 363 O ASP A 60 0.024 12.386 37.007 1.00 0.00 O ATOM 364 CB ASP A 60 -2.654 14.071 37.740 1.00 0.00 C ATOM 365 CG ASP A 60 -3.407 14.112 39.066 1.00 0.00 C ATOM 366 OD1 ASP A 60 -3.012 13.403 39.998 1.00 0.00 O ATOM 367 OD2 ASP A 60 -4.480 14.720 39.127 1.00 0.00 O ATOM 368 N ARG A 61 -0.371 14.199 35.722 1.00 0.00 N ATOM 369 CA ARG A 61 0.274 13.646 34.524 1.00 0.00 C ATOM 370 C ARG A 61 1.756 13.994 34.437 1.00 0.00 C ATOM 371 O ARG A 61 2.142 15.082 34.879 1.00 0.00 O ATOM 372 CB ARG A 61 -0.435 14.125 33.259 1.00 0.00 C ATOM 373 CG ARG A 61 -1.871 13.613 33.161 1.00 0.00 C ATOM 374 CD ARG A 61 -2.563 14.129 31.900 1.00 0.00 C ATOM 375 NE ARG A 61 -3.930 13.597 31.802 1.00 0.00 N ATOM 376 CZ ARG A 61 -4.511 13.306 30.647 1.00 0.00 C ATOM 377 NH1 ARG A 61 -5.745 12.826 30.641 1.00 0.00 N ATOM 378 NH2 ARG A 61 -4.000 13.787 29.524 1.00 0.00 N ATOM 379 N GLU A 62 2.537 12.933 34.342 1.00 0.00 N ATOM 380 CA GLU A 62 3.997 13.023 34.225 1.00 0.00 C ATOM 381 C GLU A 62 4.484 13.799 33.006 1.00 0.00 C ATOM 382 O GLU A 62 5.042 13.225 32.062 1.00 0.00 O ATOM 383 CB GLU A 62 4.615 11.634 34.291 1.00 0.00 C ATOM 384 CG GLU A 62 4.495 11.079 35.707 1.00 0.00 C ATOM 385 CD GLU A 62 4.347 9.564 35.648 1.00 0.00 C ATOM 386 OE1 GLU A 62 5.060 8.860 36.373 1.00 0.00 O ATOM 387 OE2 GLU A 62 3.366 9.093 35.060 1.00 0.00 O ATOM 388 N LEU A 63 4.435 15.107 33.175 1.00 0.00 N ATOM 389 CA LEU A 63 4.907 16.096 32.199 1.00 0.00 C ATOM 390 C LEU A 63 6.142 16.819 32.732 1.00 0.00 C ATOM 391 O LEU A 63 6.662 16.445 33.791 1.00 0.00 O ATOM 392 CB LEU A 63 3.802 17.127 31.960 1.00 0.00 C ATOM 393 CG LEU A 63 2.510 16.499 31.437 1.00 0.00 C ATOM 394 CD1 LEU A 63 1.309 17.430 31.584 1.00 0.00 C ATOM 395 CD2 LEU A 63 2.653 15.948 30.019 1.00 0.00 C ATOM 396 N THR A 64 6.742 17.628 31.883 1.00 0.00 N ATOM 397 CA THR A 64 7.889 18.451 32.285 1.00 0.00 C ATOM 398 C THR A 64 7.439 19.864 32.636 1.00 0.00 C ATOM 399 O THR A 64 6.766 20.496 31.815 1.00 0.00 O ATOM 400 CB THR A 64 8.919 18.502 31.160 1.00 0.00 C ATOM 401 OG1 THR A 64 9.400 17.184 30.922 1.00 0.00 O ATOM 402 CG2 THR A 64 10.101 19.409 31.497 1.00 0.00 C ATOM 403 N PHE A 65 7.464 20.146 33.931 1.00 0.00 N ATOM 404 CA PHE A 65 6.975 21.424 34.470 1.00 0.00 C ATOM 405 C PHE A 65 8.050 22.479 34.716 1.00 0.00 C ATOM 406 O PHE A 65 9.213 22.148 34.981 1.00 0.00 O ATOM 407 CB PHE A 65 6.248 21.214 35.800 1.00 0.00 C ATOM 408 CG PHE A 65 5.030 20.288 35.680 1.00 0.00 C ATOM 409 CD1 PHE A 65 3.859 20.747 35.099 1.00 0.00 C ATOM 410 CD2 PHE A 65 5.094 19.000 36.187 1.00 0.00 C ATOM 411 CE1 PHE A 65 2.749 19.904 34.995 1.00 0.00 C ATOM 412 CE2 PHE A 65 3.989 18.150 36.087 1.00 0.00 C ATOM 413 CZ PHE A 65 2.815 18.601 35.487 1.00 0.00 C ATOM 414 N ARG A 65A 7.668 23.712 34.409 1.00 0.00 N ATOM 415 CA ARG A 65A 8.426 24.902 34.812 1.00 0.00 C ATOM 416 C ARG A 65A 7.516 25.948 35.451 1.00 0.00 C ATOM 417 O ARG A 65A 6.290 25.876 35.292 1.00 0.00 O ATOM 418 CB ARG A 65A 9.227 25.545 33.677 1.00 0.00 C ATOM 419 CG ARG A 65A 8.406 26.509 32.821 1.00 0.00 C ATOM 420 CD ARG A 65A 9.294 27.317 31.875 1.00 0.00 C ATOM 421 NE ARG A 65A 8.485 28.283 31.122 1.00 0.00 N ATOM 422 CZ ARG A 65A 8.900 28.891 30.020 1.00 0.00 C ATOM 423 NH1 ARG A 65A 8.086 29.745 29.415 1.00 0.00 N ATOM 424 NH2 ARG A 65A 10.185 28.875 29.701 1.00 0.00 N ATOM 425 N VAL A 66 8.078 26.593 36.454 1.00 0.00 N ATOM 426 CA VAL A 66 7.408 27.653 37.212 1.00 0.00 C ATOM 427 C VAL A 66 7.955 29.034 36.865 1.00 0.00 C ATOM 428 O VAL A 66 9.149 29.150 36.559 1.00 0.00 O ATOM 429 CB VAL A 66 7.556 27.377 38.708 1.00 0.00 C ATOM 430 CG1 VAL A 66 7.203 28.575 39.587 1.00 0.00 C ATOM 431 CG2 VAL A 66 6.814 26.111 39.132 1.00 0.00 C ATOM 432 N VAL A 67 7.031 29.885 36.446 1.00 0.00 N ATOM 433 CA VAL A 67 7.388 31.258 36.085 1.00 0.00 C ATOM 434 C VAL A 67 6.862 32.291 37.077 1.00 0.00 C ATOM 435 O VAL A 67 5.655 32.327 37.350 1.00 0.00 O ATOM 436 CB VAL A 67 6.887 31.602 34.687 1.00 0.00 C ATOM 437 CG1 VAL A 67 7.546 32.884 34.185 1.00 0.00 C ATOM 438 CG2 VAL A 67 7.124 30.456 33.710 1.00 0.00 C ATOM 439 N VAL A 68 7.802 32.858 37.818 1.00 0.00 N ATOM 440 CA VAL A 68 7.496 33.944 38.756 1.00 0.00 C ATOM 441 C VAL A 68 7.707 35.306 38.098 1.00 0.00 C ATOM 442 O VAL A 68 8.378 35.380 37.061 1.00 0.00 O ATOM 443 CB VAL A 68 8.355 33.838 40.020 1.00 0.00 C ATOM 444 CG1 VAL A 68 8.085 32.564 40.812 1.00 0.00 C ATOM 445 CG2 VAL A 68 9.844 33.991 39.738 1.00 0.00 C ATOM 446 N GLY A 69 6.846 36.239 38.463 1.00 0.00 N ATOM 447 CA GLY A 69 6.922 37.611 37.947 1.00 0.00 C ATOM 448 C GLY A 69 6.201 37.772 36.613 1.00 0.00 C ATOM 449 O GLY A 69 6.712 38.465 35.724 1.00 0.00 O ATOM 450 N GLU A 70 5.323 36.822 36.357 1.00 0.00 N ATOM 451 CA GLU A 70 4.494 36.849 35.145 1.00 0.00 C ATOM 452 C GLU A 70 3.336 37.838 35.209 1.00 0.00 C ATOM 453 O GLU A 70 2.782 38.099 36.285 1.00 0.00 O ATOM 454 CB GLU A 70 3.932 35.463 34.837 1.00 0.00 C ATOM 455 CG GLU A 70 4.755 34.691 33.810 1.00 0.00 C ATOM 456 CD GLU A 70 4.406 35.118 32.383 1.00 0.00 C ATOM 457 OE1 GLU A 70 4.182 36.308 32.122 1.00 0.00 O ATOM 458 OE2 GLU A 70 4.380 34.255 31.497 1.00 0.00 O ATOM 459 N HIS A 71 2.993 38.350 34.040 1.00 0.00 N ATOM 460 CA HIS A 71 1.818 39.214 33.890 1.00 0.00 C ATOM 461 C HIS A 71 1.047 38.895 32.613 1.00 0.00 C ATOM 462 O HIS A 71 -0.077 38.383 32.675 1.00 0.00 O ATOM 463 CB HIS A 71 2.211 40.688 33.914 1.00 0.00 C ATOM 464 CG HIS A 71 0.955 41.564 34.026 1.00 0.00 C ATOM 465 ND1 HIS A 71 0.084 41.420 35.065 1.00 0.00 N ATOM 466 CD2 HIS A 71 0.493 42.532 33.214 1.00 0.00 C ATOM 467 CE1 HIS A 71 -0.926 42.321 34.894 1.00 0.00 C ATOM 468 NE2 HIS A 71 -0.675 43.013 33.743 1.00 0.00 N ATOM 469 N ASN A 72 1.791 38.908 31.516 1.00 0.00 N ATOM 470 CA ASN A 72 1.267 38.558 30.189 1.00 0.00 C ATOM 471 C ASN A 72 2.005 37.349 29.627 1.00 0.00 C ATOM 472 O ASN A 72 3.234 37.409 29.489 1.00 0.00 O ATOM 473 CB ASN A 72 1.394 39.736 29.221 1.00 0.00 C ATOM 474 CG ASN A 72 0.559 39.520 27.955 1.00 0.00 C ATOM 475 OD1 ASN A 72 0.561 38.435 27.356 1.00 0.00 O ATOM 476 ND2 ASN A 72 0.195 40.654 27.374 1.00 0.00 N ATOM 477 N LEU A 73 1.331 36.224 29.791 1.00 0.00 N ATOM 478 CA LEU A 73 1.793 34.907 29.321 1.00 0.00 C ATOM 479 C LEU A 73 2.461 34.949 27.951 1.00 0.00 C ATOM 480 O LEU A 73 3.630 34.566 27.819 1.00 0.00 O ATOM 481 CB LEU A 73 0.630 33.921 29.232 1.00 0.00 C ATOM 482 CG LEU A 73 0.010 33.567 30.581 1.00 0.00 C ATOM 483 CD1 LEU A 73 -1.197 32.648 30.399 1.00 0.00 C ATOM 484 CD2 LEU A 73 1.029 32.965 31.548 1.00 0.00 C ATOM 485 N ASN A 74 1.826 35.689 27.061 1.00 0.00 N ATOM 486 CA ASN A 74 2.246 35.726 25.655 1.00 0.00 C ATOM 487 C ASN A 74 3.200 36.870 25.339 1.00 0.00 C ATOM 488 O ASN A 74 3.529 37.094 24.168 1.00 0.00 O ATOM 489 CB ASN A 74 1.027 35.858 24.744 1.00 0.00 C ATOM 490 CG ASN A 74 0.131 34.632 24.892 1.00 0.00 C ATOM 491 OD1 ASN A 74 -1.050 34.768 25.237 1.00 0.00 O ATOM 492 ND2 ASN A 74 0.781 33.479 24.908 1.00 0.00 N ATOM 493 N GLN A 75 3.560 37.616 26.369 1.00 0.00 N ATOM 494 CA GLN A 75 4.381 38.816 26.146 1.00 0.00 C ATOM 495 C GLN A 75 5.426 39.059 27.234 1.00 0.00 C ATOM 496 O GLN A 75 5.204 38.678 28.391 1.00 0.00 O ATOM 497 CB GLN A 75 3.422 39.999 26.042 1.00 0.00 C ATOM 498 CG GLN A 75 4.055 41.328 25.650 1.00 0.00 C ATOM 499 CD GLN A 75 2.940 42.369 25.596 1.00 0.00 C ATOM 500 OE1 GLN A 75 1.797 42.020 25.269 1.00 0.00 O ATOM 501 NE2 GLN A 75 3.199 43.479 26.266 1.00 0.00 N ATOM 502 N ASN A 76 6.635 39.357 26.778 1.00 0.00 N ATOM 503 CA ASN A 76 7.767 39.666 27.659 1.00 0.00 C ATOM 504 C ASN A 76 7.517 40.864 28.567 1.00 0.00 C ATOM 505 O ASN A 76 7.250 41.972 28.083 1.00 0.00 O ATOM 506 CB ASN A 76 9.045 39.902 26.863 1.00 0.00 C ATOM 507 CG ASN A 76 10.128 40.351 27.839 1.00 0.00 C ATOM 508 OD1 ASN A 76 10.501 39.584 28.737 1.00 0.00 O ATOM 509 ND2 ASN A 76 10.295 41.663 27.884 1.00 0.00 N ATOM 510 N ASN A 77 7.289 40.535 29.825 1.00 0.00 N ATOM 511 CA ASN A 77 7.003 41.553 30.845 1.00 0.00 C ATOM 512 C ASN A 77 8.269 42.182 31.412 1.00 0.00 C ATOM 513 O ASN A 77 8.192 43.078 32.262 1.00 0.00 O ATOM 514 CB ASN A 77 6.183 40.955 31.985 1.00 0.00 C ATOM 515 CG ASN A 77 4.822 40.537 31.443 1.00 0.00 C ATOM 516 OD1 ASN A 77 4.568 39.330 31.346 1.00 0.00 O ATOM 517 ND2 ASN A 77 4.283 41.450 30.651 1.00 0.00 N ATOM 518 N GLY A 78 9.376 41.523 31.104 1.00 0.00 N ATOM 519 CA GLY A 78 10.712 41.940 31.557 1.00 0.00 C ATOM 520 C GLY A 78 10.986 41.598 33.019 1.00 0.00 C ATOM 521 O GLY A 78 12.048 41.939 33.555 1.00 0.00 O ATOM 522 N THR A 79 9.988 41.024 33.665 1.00 0.00 N ATOM 523 CA THR A 79 10.070 40.721 35.101 1.00 0.00 C ATOM 524 C THR A 79 10.018 39.232 35.426 1.00 0.00 C ATOM 525 O THR A 79 9.941 38.853 36.601 1.00 0.00 O ATOM 526 CB THR A 79 8.919 41.419 35.814 1.00 0.00 C ATOM 527 OG1 THR A 79 7.712 41.020 35.180 1.00 0.00 O ATOM 528 CG2 THR A 79 9.035 42.938 35.723 1.00 0.00 C ATOM 529 N GLU A 80 9.991 38.418 34.385 1.00 0.00 N ATOM 530 CA GLU A 80 9.866 36.963 34.547 1.00 0.00 C ATOM 531 C GLU A 80 11.162 36.244 34.921 1.00 0.00 C ATOM 532 O GLU A 80 12.247 36.818 34.767 1.00 0.00 O ATOM 533 CB GLU A 80 9.300 36.315 33.283 1.00 0.00 C ATOM 534 CG GLU A 80 7.969 36.913 32.826 1.00 0.00 C ATOM 535 CD GLU A 80 8.200 37.919 31.699 1.00 0.00 C ATOM 536 OE1 GLU A 80 8.938 38.893 31.883 1.00 0.00 O ATOM 537 OE2 GLU A 80 7.616 37.755 30.621 1.00 0.00 O ATOM 538 N GLN A 81 10.972 35.270 35.801 1.00 0.00 N ATOM 539 CA GLN A 81 11.982 34.266 36.177 1.00 0.00 C ATOM 540 C GLN A 81 11.495 32.847 35.895 1.00 0.00 C ATOM 541 O GLN A 81 10.441 32.432 36.393 1.00 0.00 O ATOM 542 CB GLN A 81 12.413 34.364 37.641 1.00 0.00 C ATOM 543 CG GLN A 81 13.423 35.475 37.918 1.00 0.00 C ATOM 544 CD GLN A 81 13.762 35.494 39.408 1.00 0.00 C ATOM 545 OE1 GLN A 81 14.423 34.579 39.920 1.00 0.00 O ATOM 546 NE2 GLN A 81 13.193 36.470 40.095 1.00 0.00 N ATOM 547 N TYR A 82 12.243 32.172 35.042 1.00 0.00 N ATOM 548 CA TYR A 82 11.929 30.816 34.578 1.00 0.00 C ATOM 549 C TYR A 82 12.757 29.763 35.313 1.00 0.00 C ATOM 550 O TYR A 82 13.991 29.858 35.330 1.00 0.00 O ATOM 551 CB TYR A 82 12.231 30.718 33.081 1.00 0.00 C ATOM 552 CG TYR A 82 11.497 31.791 32.258 1.00 0.00 C ATOM 553 CD1 TYR A 82 12.178 32.912 31.806 1.00 0.00 C ATOM 554 CD2 TYR A 82 10.159 31.624 31.942 1.00 0.00 C ATOM 555 CE1 TYR A 82 11.514 33.883 31.046 1.00 0.00 C ATOM 556 CE2 TYR A 82 9.487 32.588 31.179 1.00 0.00 C ATOM 557 CZ TYR A 82 10.166 33.718 30.731 1.00 0.00 C ATOM 558 OH TYR A 82 9.447 34.789 30.238 1.00 0.00 O ATOM 559 N VAL A 83 12.079 28.976 36.134 1.00 0.00 N ATOM 560 CA VAL A 83 12.748 27.925 36.920 1.00 0.00 C ATOM 561 C VAL A 83 12.071 26.560 36.784 1.00 0.00 C ATOM 562 O VAL A 83 10.872 26.498 36.492 1.00 0.00 O ATOM 563 CB VAL A 83 12.813 28.354 38.391 1.00 0.00 C ATOM 564 CG1 VAL A 83 11.432 28.490 39.028 1.00 0.00 C ATOM 565 CG2 VAL A 83 13.743 27.485 39.235 1.00 0.00 C ATOM 566 N GLY A 84 12.888 25.518 36.700 1.00 0.00 N ATOM 567 CA GLY A 84 12.400 24.135 36.598 1.00 0.00 C ATOM 568 C GLY A 84 12.061 23.521 37.956 1.00 0.00 C ATOM 569 O GLY A 84 12.323 24.130 39.000 1.00 0.00 O ATOM 570 N VAL A 85 11.223 22.501 37.895 1.00 0.00 N ATOM 571 CA VAL A 85 10.757 21.769 39.082 1.00 0.00 C ATOM 572 C VAL A 85 11.572 20.497 39.308 1.00 0.00 C ATOM 573 O VAL A 85 11.672 19.674 38.390 1.00 0.00 O ATOM 574 CB VAL A 85 9.284 21.404 38.881 1.00 0.00 C ATOM 575 CG1 VAL A 85 8.728 20.541 40.012 1.00 0.00 C ATOM 576 CG2 VAL A 85 8.416 22.637 38.633 1.00 0.00 C ATOM 577 N GLN A 86 12.376 20.491 40.366 1.00 0.00 N ATOM 578 CA GLN A 86 13.222 19.315 40.622 1.00 0.00 C ATOM 579 C GLN A 86 12.514 18.201 41.389 1.00 0.00 C ATOM 580 O GLN A 86 12.809 17.021 41.158 1.00 0.00 O ATOM 581 CB GLN A 86 14.547 19.650 41.319 1.00 0.00 C ATOM 582 CG GLN A 86 14.425 19.837 42.834 1.00 0.00 C ATOM 583 CD GLN A 86 15.814 19.868 43.468 1.00 0.00 C ATOM 584 OE1 GLN A 86 16.668 20.651 43.033 1.00 0.00 O ATOM 585 NE2 GLN A 86 16.105 18.809 44.211 1.00 0.00 N ATOM 586 N LYS A 87 11.472 18.563 42.123 1.00 0.00 N ATOM 587 CA LYS A 87 10.825 17.590 43.015 1.00 0.00 C ATOM 588 C LYS A 87 9.357 17.894 43.308 1.00 0.00 C ATOM 589 O LYS A 87 8.987 19.066 43.440 1.00 0.00 O ATOM 590 CB LYS A 87 11.631 17.506 44.312 1.00 0.00 C ATOM 591 CG LYS A 87 11.153 16.386 45.231 1.00 0.00 C ATOM 592 CD LYS A 87 12.082 16.180 46.422 1.00 0.00 C ATOM 593 CE LYS A 87 11.592 15.045 47.317 1.00 0.00 C ATOM 594 NZ LYS A 87 11.477 13.803 46.542 1.00 0.00 N ATOM 595 N ILE A 88 8.523 16.888 43.078 1.00 0.00 N ATOM 596 CA ILE A 88 7.067 16.985 43.256 1.00 0.00 C ATOM 597 C ILE A 88 6.543 16.115 44.399 1.00 0.00 C ATOM 598 O ILE A 88 6.863 14.922 44.463 1.00 0.00 O ATOM 599 CB ILE A 88 6.377 16.581 41.952 1.00 0.00 C ATOM 600 CG1 ILE A 88 6.830 17.443 40.775 1.00 0.00 C ATOM 601 CG2 ILE A 88 4.855 16.545 42.077 1.00 0.00 C ATOM 602 CD1 ILE A 88 6.153 17.035 39.469 1.00 0.00 C ATOM 603 N VAL A 89 6.030 16.788 45.419 1.00 0.00 N ATOM 604 CA VAL A 89 5.454 16.124 46.596 1.00 0.00 C ATOM 605 C VAL A 89 3.939 16.294 46.684 1.00 0.00 C ATOM 606 O VAL A 89 3.453 17.394 46.971 1.00 0.00 O ATOM 607 CB VAL A 89 6.080 16.671 47.879 1.00 0.00 C ATOM 608 CG1 VAL A 89 5.583 15.917 49.112 1.00 0.00 C ATOM 609 CG2 VAL A 89 7.606 16.680 47.814 1.00 0.00 C ATOM 610 N VAL A 90 3.233 15.282 46.218 1.00 0.00 N ATOM 611 CA VAL A 90 1.768 15.244 46.294 1.00 0.00 C ATOM 612 C VAL A 90 1.308 14.585 47.594 1.00 0.00 C ATOM 613 O VAL A 90 2.090 13.818 48.170 1.00 0.00 O ATOM 614 CB VAL A 90 1.232 14.478 45.083 1.00 0.00 C ATOM 615 CG1 VAL A 90 1.958 13.154 44.858 1.00 0.00 C ATOM 616 CG2 VAL A 90 -0.284 14.309 45.089 1.00 0.00 C ATOM 617 N HIS A 91 0.351 15.248 48.238 1.00 0.00 N ATOM 618 CA HIS A 91 -0.248 14.762 49.493 1.00 0.00 C ATOM 619 C HIS A 91 -0.636 13.285 49.407 1.00 0.00 C ATOM 620 O HIS A 91 -1.205 12.869 48.390 1.00 0.00 O ATOM 621 CB HIS A 91 -1.476 15.599 49.852 1.00 0.00 C ATOM 622 CG HIS A 91 -1.871 15.369 51.319 1.00 0.00 C ATOM 623 ND1 HIS A 91 -2.390 14.187 51.755 1.00 0.00 N ATOM 624 CD2 HIS A 91 -1.773 16.198 52.369 1.00 0.00 C ATOM 625 CE1 HIS A 91 -2.615 14.294 53.100 1.00 0.00 C ATOM 626 NE2 HIS A 91 -2.232 15.547 53.480 1.00 0.00 N ATOM 627 N PRO A 92 0.019 12.491 50.246 1.00 0.00 N ATOM 628 CA PRO A 92 -0.108 11.019 50.318 1.00 0.00 C ATOM 629 C PRO A 92 -1.524 10.449 50.234 1.00 0.00 C ATOM 630 O PRO A 92 -1.698 9.328 49.741 1.00 0.00 O ATOM 631 CB PRO A 92 0.585 10.591 51.611 1.00 0.00 C ATOM 632 CG PRO A 92 0.850 11.883 52.368 1.00 0.00 C ATOM 633 CD PRO A 92 0.973 12.940 51.278 1.00 0.00 C ATOM 634 N TYR A 93 -2.514 11.288 50.487 1.00 0.00 N ATOM 635 CA TYR A 93 -3.923 10.872 50.423 1.00 0.00 C ATOM 636 C TYR A 93 -4.625 11.286 49.131 1.00 0.00 C ATOM 637 O TYR A 93 -5.791 10.925 48.922 1.00 0.00 O ATOM 638 CB TYR A 93 -4.729 11.373 51.623 1.00 0.00 C ATOM 639 CG TYR A 93 -4.456 10.605 52.928 1.00 0.00 C ATOM 640 CD1 TYR A 93 -3.910 9.331 52.899 1.00 0.00 C ATOM 641 CD2 TYR A 93 -4.802 11.178 54.141 1.00 0.00 C ATOM 642 CE1 TYR A 93 -3.681 8.635 54.093 1.00 0.00 C ATOM 643 CE2 TYR A 93 -4.579 10.490 55.339 1.00 0.00 C ATOM 644 CZ TYR A 93 -4.013 9.216 55.317 1.00 0.00 C ATOM 645 OH TYR A 93 -4.212 8.391 56.404 1.00 0.00 O ATOM 646 N TRP A 94 -3.904 11.996 48.269 1.00 0.00 N ATOM 647 CA TRP A 94 -4.473 12.415 46.974 1.00 0.00 C ATOM 648 C TRP A 94 -4.760 11.249 46.031 1.00 0.00 C ATOM 649 O TRP A 94 -3.999 10.273 46.026 1.00 0.00 O ATOM 650 CB TRP A 94 -3.651 13.509 46.281 1.00 0.00 C ATOM 651 CG TRP A 94 -4.100 13.773 44.830 1.00 0.00 C ATOM 652 CD1 TRP A 94 -3.470 13.459 43.676 1.00 0.00 C ATOM 653 CD2 TRP A 94 -5.267 14.428 44.428 1.00 0.00 C ATOM 654 NE1 TRP A 94 -4.208 13.875 42.587 1.00 0.00 N ATOM 655 CE2 TRP A 94 -5.268 14.443 43.011 1.00 0.00 C ATOM 656 CE3 TRP A 94 -6.306 14.982 45.158 1.00 0.00 C ATOM 657 CZ2 TRP A 94 -6.296 14.987 42.260 1.00 0.00 C ATOM 658 CZ3 TRP A 94 -7.347 15.540 44.402 1.00 0.00 C ATOM 659 CH2 TRP A 94 -7.342 15.542 43.002 1.00 0.00 C ATOM 660 N ASN A 95 -6.055 11.147 45.794 1.00 0.00 N ATOM 661 CA ASN A 95 -6.680 10.169 44.898 1.00 0.00 C ATOM 662 C ASN A 95 -7.447 10.837 43.759 1.00 0.00 C ATOM 663 O ASN A 95 -8.402 11.574 44.033 1.00 0.00 O ATOM 664 CB ASN A 95 -7.625 9.296 45.718 1.00 0.00 C ATOM 665 CG ASN A 95 -8.506 8.455 44.798 1.00 0.00 C ATOM 666 OD1 ASN A 95 -9.603 8.059 45.210 1.00 0.00 O ATOM 667 ND2 ASN A 95 -7.907 7.967 43.724 1.00 0.00 N ATOM 668 N THR A 96 -6.731 10.937 42.648 1.00 0.00 N ATOM 669 CA THR A 96 -7.162 11.569 41.388 1.00 0.00 C ATOM 670 C THR A 96 -8.637 11.360 41.051 1.00 0.00 C ATOM 671 O THR A 96 -9.314 12.280 40.575 1.00 0.00 O ATOM 672 CB THR A 96 -6.301 11.051 40.235 1.00 0.00 C ATOM 673 OG1 THR A 96 -4.929 11.087 40.610 1.00 0.00 O ATOM 674 CG2 THR A 96 -6.499 11.846 38.945 1.00 0.00 C ATOM 675 N ASP A 97 -9.113 10.157 41.319 1.00 0.00 N ATOM 676 CA ASP A 97 -10.493 9.794 40.982 1.00 0.00 C ATOM 677 C ASP A 97 -11.503 10.329 41.989 1.00 0.00 C ATOM 678 O ASP A 97 -12.715 10.155 41.813 1.00 0.00 O ATOM 679 CB ASP A 97 -10.628 8.278 40.875 1.00 0.00 C ATOM 680 CG ASP A 97 -9.646 7.775 39.822 1.00 0.00 C ATOM 681 OD1 ASP A 97 -9.415 8.490 38.840 1.00 0.00 O ATOM 682 OD2 ASP A 97 -8.926 6.807 40.093 1.00 0.00 O ATOM 683 N ASP A 98 -10.982 10.840 43.089 1.00 0.00 N ATOM 684 CA ASP A 98 -11.858 11.371 44.140 1.00 0.00 C ATOM 685 C ASP A 98 -11.425 12.754 44.619 1.00 0.00 C ATOM 686 O ASP A 98 -10.800 12.879 45.679 1.00 0.00 O ATOM 687 CB ASP A 98 -11.891 10.399 45.316 1.00 0.00 C ATOM 688 CG ASP A 98 -13.180 10.571 46.117 1.00 0.00 C ATOM 689 OD1 ASP A 98 -13.910 11.547 45.901 1.00 0.00 O ATOM 690 OD2 ASP A 98 -13.551 9.641 46.844 1.00 0.00 O ATOM 691 N VAL A 99 -11.543 13.717 43.722 1.00 0.00 N ATOM 692 CA VAL A 99 -11.178 15.101 44.049 1.00 0.00 C ATOM 693 C VAL A 99 -12.121 15.687 45.098 1.00 0.00 C ATOM 694 O VAL A 99 -11.664 16.435 45.973 1.00 0.00 O ATOM 695 CB VAL A 99 -11.153 15.984 42.797 1.00 0.00 C ATOM 696 CG1 VAL A 99 -10.570 15.230 41.604 1.00 0.00 C ATOM 697 CG2 VAL A 99 -12.515 16.579 42.443 1.00 0.00 C ATOM 698 N ALA A 99A -13.223 14.968 45.263 1.00 0.00 N ATOM 699 CA ALA A 99A -14.281 15.336 46.205 1.00 0.00 C ATOM 700 C ALA A 99A -13.908 14.916 47.620 1.00 0.00 C ATOM 701 O ALA A 99A -14.311 15.580 48.582 1.00 0.00 O ATOM 702 CB ALA A 99A -15.598 14.678 45.801 1.00 0.00 C ATOM 703 N ALA A 99B -12.853 14.116 47.664 1.00 0.00 N ATOM 704 CA ALA A 99B -12.305 13.657 48.946 1.00 0.00 C ATOM 705 C ALA A 99B -11.352 14.682 49.551 1.00 0.00 C ATOM 706 O ALA A 99B -11.244 14.781 50.780 1.00 0.00 O ATOM 707 CB ALA A 99B -11.585 12.322 48.788 1.00 0.00 C ATOM 708 N GLY A 100 -10.876 15.568 48.690 1.00 0.00 N ATOM 709 CA GLY A 100 -9.966 16.648 49.106 1.00 0.00 C ATOM 710 C GLY A 100 -8.503 16.360 48.781 1.00 0.00 C ATOM 711 O GLY A 100 -8.241 15.534 47.898 1.00 0.00 O ATOM 712 N TYR A 101 -7.656 16.730 49.740 1.00 0.00 N ATOM 713 CA TYR A 101 -6.188 16.562 49.721 1.00 0.00 C ATOM 714 C TYR A 101 -5.529 17.024 48.421 1.00 0.00 C ATOM 715 O TYR A 101 -4.418 16.586 48.094 1.00 0.00 O ATOM 716 CB TYR A 101 -5.807 15.103 49.995 1.00 0.00 C ATOM 717 CG TYR A 101 -6.493 14.555 51.258 1.00 0.00 C ATOM 718 CD1 TYR A 101 -6.084 14.975 52.513 1.00 0.00 C ATOM 719 CD2 TYR A 101 -7.521 13.631 51.139 1.00 0.00 C ATOM 720 CE1 TYR A 101 -6.710 14.479 53.662 1.00 0.00 C ATOM 721 CE2 TYR A 101 -8.153 13.129 52.281 1.00 0.00 C ATOM 722 CZ TYR A 101 -7.747 13.556 53.542 1.00 0.00 C ATOM 723 OH TYR A 101 -8.429 13.135 54.664 1.00 0.00 O ATOM 724 N ASP A 102 -6.208 17.933 47.734 1.00 0.00 N ATOM 725 CA ASP A 102 -5.750 18.476 46.446 1.00 0.00 C ATOM 726 C ASP A 102 -4.710 19.581 46.620 1.00 0.00 C ATOM 727 O ASP A 102 -5.042 20.772 46.557 1.00 0.00 O ATOM 728 CB ASP A 102 -6.944 18.992 45.641 1.00 0.00 C ATOM 729 CG ASP A 102 -6.519 19.337 44.213 1.00 0.00 C ATOM 730 OD1 ASP A 102 -5.434 18.928 43.785 1.00 0.00 O ATOM 731 OD2 ASP A 102 -7.325 19.910 43.470 1.00 0.00 O ATOM 732 N ILE A 103 -3.586 19.163 47.171 1.00 0.00 N ATOM 733 CA ILE A 103 -2.436 20.043 47.406 1.00 0.00 C ATOM 734 C ILE A 103 -1.097 19.347 47.153 1.00 0.00 C ATOM 735 O ILE A 103 -1.015 18.120 47.300 1.00 0.00 O ATOM 736 CB ILE A 103 -2.502 20.612 48.828 1.00 0.00 C ATOM 737 CG1 ILE A 103 -1.398 21.626 49.128 1.00 0.00 C ATOM 738 CG2 ILE A 103 -2.603 19.525 49.898 1.00 0.00 C ATOM 739 CD1 ILE A 103 -1.498 22.182 50.546 1.00 0.00 C ATOM 740 N ALA A 104 -0.272 20.027 46.367 1.00 0.00 N ATOM 741 CA ALA A 104 1.094 19.575 46.070 1.00 0.00 C ATOM 742 C ALA A 104 2.149 20.658 46.285 1.00 0.00 C ATOM 743 O ALA A 104 1.815 21.848 46.343 1.00 0.00 O ATOM 744 CB ALA A 104 1.189 19.053 44.639 1.00 0.00 C ATOM 745 N LEU A 105 3.321 20.199 46.694 1.00 0.00 N ATOM 746 CA LEU A 105 4.499 21.053 46.901 1.00 0.00 C ATOM 747 C LEU A 105 5.615 20.743 45.906 1.00 0.00 C ATOM 748 O LEU A 105 5.833 19.573 45.570 1.00 0.00 O ATOM 749 CB LEU A 105 5.030 20.928 48.329 1.00 0.00 C ATOM 750 CG LEU A 105 4.076 21.488 49.385 1.00 0.00 C ATOM 751 CD1 LEU A 105 4.611 21.270 50.800 1.00 0.00 C ATOM 752 CD2 LEU A 105 3.747 22.959 49.141 1.00 0.00 C ATOM 753 N LEU A 106 6.080 21.791 45.245 1.00 0.00 N ATOM 754 CA LEU A 106 7.111 21.676 44.203 1.00 0.00 C ATOM 755 C LEU A 106 8.433 22.326 44.601 1.00 0.00 C ATOM 756 O LEU A 106 8.523 23.559 44.675 1.00 0.00 O ATOM 757 CB LEU A 106 6.652 22.352 42.910 1.00 0.00 C ATOM 758 CG LEU A 106 5.274 21.910 42.418 1.00 0.00 C ATOM 759 CD1 LEU A 106 4.835 22.734 41.209 1.00 0.00 C ATOM 760 CD2 LEU A 106 5.190 20.410 42.137 1.00 0.00 C ATOM 761 N ARG A 107 9.442 21.495 44.803 1.00 0.00 N ATOM 762 CA ARG A 107 10.789 22.012 45.062 1.00 0.00 C ATOM 763 C ARG A 107 11.502 22.390 43.770 1.00 0.00 C ATOM 764 O ARG A 107 11.527 21.579 42.835 1.00 0.00 O ATOM 765 CB ARG A 107 11.656 21.040 45.859 1.00 0.00 C ATOM 766 CG ARG A 107 13.064 21.610 46.026 1.00 0.00 C ATOM 767 CD ARG A 107 14.001 20.717 46.835 1.00 0.00 C ATOM 768 NE ARG A 107 15.364 21.267 46.755 1.00 0.00 N ATOM 769 CZ ARG A 107 16.016 21.793 47.784 1.00 0.00 C ATOM 770 NH1 ARG A 107 17.235 22.271 47.590 1.00 0.00 N ATOM 771 NH2 ARG A 107 15.639 21.492 49.017 1.00 0.00 N ATOM 772 N LEU A 108 11.567 23.699 43.593 1.00 0.00 N ATOM 773 CA LEU A 108 12.231 24.326 42.445 1.00 0.00 C ATOM 774 C LEU A 108 13.718 23.989 42.371 1.00 0.00 C ATOM 775 O LEU A 108 14.383 23.862 43.409 1.00 0.00 O ATOM 776 CB LEU A 108 12.080 25.843 42.513 1.00 0.00 C ATOM 777 CG LEU A 108 10.621 26.291 42.545 1.00 0.00 C ATOM 778 CD1 LEU A 108 10.505 27.800 42.755 1.00 0.00 C ATOM 779 CD2 LEU A 108 9.850 25.825 41.312 1.00 0.00 C ATOM 780 N ALA A 109 14.175 23.779 41.146 1.00 0.00 N ATOM 781 CA ALA A 109 15.575 23.468 40.822 1.00 0.00 C ATOM 782 C ALA A 109 16.564 24.491 41.377 1.00 0.00 C ATOM 783 O ALA A 109 17.678 24.128 41.776 1.00 0.00 O ATOM 784 CB ALA A 109 15.748 23.373 39.309 1.00 0.00 C ATOM 785 N GLN A 110 16.058 25.695 41.585 1.00 0.00 N ATOM 786 CA GLN A 110 16.841 26.811 42.129 1.00 0.00 C ATOM 787 C GLN A 110 15.949 27.859 42.793 1.00 0.00 C ATOM 788 O GLN A 110 14.750 27.934 42.501 1.00 0.00 O ATOM 789 CB GLN A 110 17.653 27.458 41.007 1.00 0.00 C ATOM 790 CG GLN A 110 19.104 27.713 41.416 1.00 0.00 C ATOM 791 CD GLN A 110 19.855 28.366 40.259 1.00 0.00 C ATOM 792 OE1 GLN A 110 19.239 29.050 39.431 1.00 0.00 O ATOM 793 NE2 GLN A 110 21.173 28.372 40.386 1.00 0.00 N ATOM 794 N SER A 111 16.558 28.698 43.614 1.00 0.00 N ATOM 795 CA SER A 111 15.828 29.759 44.312 1.00 0.00 C ATOM 796 C SER A 111 15.646 31.016 43.470 1.00 0.00 C ATOM 797 O SER A 111 16.603 31.514 42.865 1.00 0.00 O ATOM 798 CB SER A 111 16.505 30.113 45.632 1.00 0.00 C ATOM 799 OG SER A 111 16.425 28.995 46.508 1.00 0.00 O ATOM 800 N VAL A 112 14.461 31.586 43.599 1.00 0.00 N ATOM 801 CA VAL A 112 14.094 32.803 42.868 1.00 0.00 C ATOM 802 C VAL A 112 14.485 34.070 43.623 1.00 0.00 C ATOM 803 O VAL A 112 14.851 34.005 44.803 1.00 0.00 O ATOM 804 CB VAL A 112 12.593 32.823 42.585 1.00 0.00 C ATOM 805 CG1 VAL A 112 12.160 31.634 41.729 1.00 0.00 C ATOM 806 CG2 VAL A 112 11.767 32.929 43.864 1.00 0.00 C ATOM 807 N THR A 113 14.714 35.112 42.847 1.00 0.00 N ATOM 808 CA THR A 113 15.102 36.407 43.410 1.00 0.00 C ATOM 809 C THR A 113 13.903 37.309 43.685 1.00 0.00 C ATOM 810 O THR A 113 13.053 37.498 42.805 1.00 0.00 O ATOM 811 CB THR A 113 16.102 37.104 42.492 1.00 0.00 C ATOM 812 OG1 THR A 113 17.233 36.257 42.330 1.00 0.00 O ATOM 813 CG2 THR A 113 16.556 38.453 43.047 1.00 0.00 C ATOM 814 N LEU A 114 13.666 37.461 44.976 1.00 0.00 N ATOM 815 CA LEU A 114 12.553 38.264 45.487 1.00 0.00 C ATOM 816 C LEU A 114 12.718 39.759 45.234 1.00 0.00 C ATOM 817 O LEU A 114 13.848 40.265 45.255 1.00 0.00 O ATOM 818 CB LEU A 114 12.353 38.051 46.987 1.00 0.00 C ATOM 819 CG LEU A 114 12.070 36.599 47.369 1.00 0.00 C ATOM 820 CD1 LEU A 114 11.945 36.442 48.883 1.00 0.00 C ATOM 821 CD2 LEU A 114 10.848 36.031 46.651 1.00 0.00 C ATOM 822 N ASN A 115 11.706 40.270 44.558 1.00 0.00 N ATOM 823 CA ASN A 115 11.518 41.702 44.303 1.00 0.00 C ATOM 824 C ASN A 115 10.060 42.121 44.449 1.00 0.00 C ATOM 825 O ASN A 115 9.225 41.293 44.833 1.00 0.00 O ATOM 826 CB ASN A 115 12.087 42.135 42.952 1.00 0.00 C ATOM 827 CG ASN A 115 11.675 41.145 41.868 1.00 0.00 C ATOM 828 OD1 ASN A 115 10.478 40.886 41.697 1.00 0.00 O ATOM 829 ND2 ASN A 115 12.643 40.295 41.553 1.00 0.00 N ATOM 830 N SER A 116 9.743 43.250 43.853 1.00 0.00 N ATOM 831 CA SER A 116 8.390 43.812 43.946 1.00 0.00 C ATOM 832 C SER A 116 7.390 43.094 43.047 1.00 0.00 C ATOM 833 O SER A 116 6.187 43.093 43.339 1.00 0.00 O ATOM 834 CB SER A 116 8.414 45.304 43.635 1.00 0.00 C ATOM 835 OG SER A 116 9.055 45.504 42.384 1.00 0.00 O ATOM 836 N TYR A 117 7.946 42.207 42.245 1.00 0.00 N ATOM 837 CA TYR A 117 7.151 41.380 41.329 1.00 0.00 C ATOM 838 C TYR A 117 7.112 39.930 41.802 1.00 0.00 C ATOM 839 O TYR A 117 6.288 39.135 41.332 1.00 0.00 O ATOM 840 CB TYR A 117 7.712 41.444 39.905 1.00 0.00 C ATOM 841 CG TYR A 117 7.807 42.891 39.392 1.00 0.00 C ATOM 842 CD1 TYR A 117 6.663 43.569 38.999 1.00 0.00 C ATOM 843 CD2 TYR A 117 9.042 43.516 39.315 1.00 0.00 C ATOM 844 CE1 TYR A 117 6.749 44.890 38.540 1.00 0.00 C ATOM 845 CE2 TYR A 117 9.139 44.835 38.858 1.00 0.00 C ATOM 846 CZ TYR A 117 7.990 45.524 38.474 1.00 0.00 C ATOM 847 OH TYR A 117 8.114 46.695 37.757 1.00 0.00 O ATOM 848 N VAL A 118 8.081 39.591 42.646 1.00 0.00 N ATOM 849 CA VAL A 118 8.214 38.230 43.197 1.00 0.00 C ATOM 850 C VAL A 118 8.385 38.211 44.715 1.00 0.00 C ATOM 851 O VAL A 118 9.339 38.817 45.216 1.00 0.00 O ATOM 852 CB VAL A 118 9.410 37.510 42.567 1.00 0.00 C ATOM 853 CG1 VAL A 118 9.607 36.110 43.145 1.00 0.00 C ATOM 854 CG2 VAL A 118 9.351 37.473 41.042 1.00 0.00 C ATOM 855 N GLN A 119 7.294 37.921 45.408 1.00 0.00 N ATOM 856 CA GLN A 119 7.316 37.768 46.872 1.00 0.00 C ATOM 857 C GLN A 119 6.828 36.409 47.366 1.00 0.00 C ATOM 858 O GLN A 119 6.264 35.626 46.593 1.00 0.00 O ATOM 859 CB GLN A 119 6.526 38.873 47.574 1.00 0.00 C ATOM 860 CG GLN A 119 7.281 40.200 47.645 1.00 0.00 C ATOM 861 CD GLN A 119 8.523 40.042 48.522 1.00 0.00 C ATOM 862 OE1 GLN A 119 9.560 40.656 48.235 1.00 0.00 O ATOM 863 NE2 GLN A 119 8.310 39.473 49.700 1.00 0.00 N ATOM 864 N LEU A 120 6.942 36.218 48.671 1.00 0.00 N ATOM 865 CA LEU A 120 6.454 34.990 49.308 1.00 0.00 C ATOM 866 C LEU A 120 5.009 35.133 49.774 1.00 0.00 C ATOM 867 O LEU A 120 4.549 36.247 50.055 1.00 0.00 O ATOM 868 CB LEU A 120 7.313 34.562 50.499 1.00 0.00 C ATOM 869 CG LEU A 120 8.756 34.231 50.124 1.00 0.00 C ATOM 870 CD1 LEU A 120 9.511 33.648 51.317 1.00 0.00 C ATOM 871 CD2 LEU A 120 8.830 33.295 48.921 1.00 0.00 C ATOM 872 N GLY A 121 4.282 34.049 49.595 1.00 0.00 N ATOM 873 CA GLY A 121 2.866 33.964 49.959 1.00 0.00 C ATOM 874 C GLY A 121 2.672 33.706 51.449 1.00 0.00 C ATOM 875 O GLY A 121 3.413 32.905 52.033 1.00 0.00 O ATOM 876 N VAL A 122 2.037 34.683 52.066 1.00 0.00 N ATOM 877 CA VAL A 122 1.718 34.624 53.494 1.00 0.00 C ATOM 878 C VAL A 122 0.660 33.568 53.803 1.00 0.00 C ATOM 879 O VAL A 122 -0.374 33.522 53.124 1.00 0.00 O ATOM 880 CB VAL A 122 1.247 35.991 53.984 1.00 0.00 C ATOM 881 CG1 VAL A 122 0.814 35.957 55.448 1.00 0.00 C ATOM 882 CG2 VAL A 122 2.296 37.072 53.733 1.00 0.00 C ATOM 883 N LEU A 123 1.135 32.522 54.454 1.00 0.00 N ATOM 884 CA LEU A 123 0.274 31.416 54.894 1.00 0.00 C ATOM 885 C LEU A 123 -0.440 31.729 56.206 1.00 0.00 C ATOM 886 O LEU A 123 0.065 32.512 57.020 1.00 0.00 O ATOM 887 CB LEU A 123 1.097 30.141 55.066 1.00 0.00 C ATOM 888 CG LEU A 123 1.693 29.648 53.749 1.00 0.00 C ATOM 889 CD1 LEU A 123 2.615 28.449 53.961 1.00 0.00 C ATOM 890 CD2 LEU A 123 0.613 29.354 52.708 1.00 0.00 C ATOM 891 N PRO A 124 -1.666 31.243 56.311 1.00 0.00 N ATOM 892 CA PRO A 124 -2.523 31.393 57.504 1.00 0.00 C ATOM 893 C PRO A 124 -2.102 30.505 58.672 1.00 0.00 C ATOM 894 O PRO A 124 -1.225 29.643 58.535 1.00 0.00 O ATOM 895 CB PRO A 124 -3.903 30.944 57.041 1.00 0.00 C ATOM 896 CG PRO A 124 -3.616 29.921 55.957 1.00 0.00 C ATOM 897 CD PRO A 124 -2.369 30.464 55.270 1.00 0.00 C ATOM 898 N ARG A 125 -2.599 30.882 59.836 1.00 0.00 N ATOM 899 CA ARG A 125 -2.427 30.102 61.064 1.00 0.00 C ATOM 900 C ARG A 125 -3.237 28.809 60.991 1.00 0.00 C ATOM 901 O ARG A 125 -4.232 28.763 60.256 1.00 0.00 O ATOM 902 CB ARG A 125 -2.903 30.929 62.260 1.00 0.00 C ATOM 903 CG ARG A 125 -2.818 30.164 63.580 1.00 0.00 C ATOM 904 CD ARG A 125 -3.424 30.942 64.745 1.00 0.00 C ATOM 905 NE ARG A 125 -3.354 30.140 65.975 1.00 0.00 N ATOM 906 CZ ARG A 125 -4.346 30.053 66.850 1.00 0.00 C ATOM 907 NH1 ARG A 125 -4.194 29.303 67.931 1.00 0.00 N ATOM 908 NH2 ARG A 125 -5.330 30.938 66.810 1.00 0.00 N ATOM 909 N ALA A 126 -2.551 27.731 61.316 1.00 0.00 N ATOM 910 CA ALA A 126 -3.148 26.394 61.359 1.00 0.00 C ATOM 911 C ALA A 126 -4.500 26.340 62.072 1.00 0.00 C ATOM 912 O ALA A 126 -4.675 26.988 63.112 1.00 0.00 O ATOM 913 CB ALA A 126 -2.184 25.410 62.018 1.00 0.00 C ATOM 914 N GLY A 127 -5.489 25.958 61.283 1.00 0.00 N ATOM 915 CA GLY A 127 -6.853 25.707 61.771 1.00 0.00 C ATOM 916 C GLY A 127 -7.791 26.901 61.627 1.00 0.00 C ATOM 917 O GLY A 127 -8.984 26.790 61.938 1.00 0.00 O ATOM 918 N THR A 128 -7.289 27.928 60.966 1.00 0.00 N ATOM 919 CA THR A 128 -8.044 29.176 60.774 1.00 0.00 C ATOM 920 C THR A 128 -9.202 29.076 59.782 1.00 0.00 C ATOM 921 O THR A 128 -9.034 28.533 58.683 1.00 0.00 O ATOM 922 CB THR A 128 -7.101 30.305 60.369 1.00 0.00 C ATOM 923 OG1 THR A 128 -6.140 30.483 61.401 1.00 0.00 O ATOM 924 CG2 THR A 128 -7.833 31.626 60.141 1.00 0.00 C ATOM 925 N ILE A 129 -10.392 29.240 60.340 1.00 0.00 N ATOM 926 CA ILE A 129 -11.645 29.262 59.570 1.00 0.00 C ATOM 927 C ILE A 129 -12.176 30.688 59.451 1.00 0.00 C ATOM 928 O ILE A 129 -12.210 31.415 60.452 1.00 0.00 O ATOM 929 CB ILE A 129 -12.715 28.439 60.291 1.00 0.00 C ATOM 930 CG1 ILE A 129 -12.210 27.072 60.739 1.00 0.00 C ATOM 931 CG2 ILE A 129 -13.982 28.297 59.447 1.00 0.00 C ATOM 932 CD1 ILE A 129 -11.926 26.156 59.554 1.00 0.00 C ATOM 933 N LEU A 130 -12.387 31.131 58.224 1.00 0.00 N ATOM 934 CA LEU A 130 -12.978 32.453 57.984 1.00 0.00 C ATOM 935 C LEU A 130 -14.487 32.453 58.199 1.00 0.00 C ATOM 936 O LEU A 130 -15.159 31.474 57.852 1.00 0.00 O ATOM 937 CB LEU A 130 -12.703 32.919 56.558 1.00 0.00 C ATOM 938 CG LEU A 130 -11.227 33.205 56.310 1.00 0.00 C ATOM 939 CD1 LEU A 130 -10.955 33.468 54.832 1.00 0.00 C ATOM 940 CD2 LEU A 130 -10.709 34.337 57.195 1.00 0.00 C ATOM 941 N ALA A 131 -14.997 33.650 58.419 1.00 0.00 N ATOM 942 CA ALA A 131 -16.437 33.863 58.570 1.00 0.00 C ATOM 943 C ALA A 131 -17.100 34.009 57.206 1.00 0.00 C ATOM 944 O ALA A 131 -16.400 34.079 56.189 1.00 0.00 O ATOM 945 CB ALA A 131 -16.696 35.123 59.392 1.00 0.00 C ATOM 946 N ASN A 132 -18.383 33.712 57.173 1.00 0.00 N ATOM 947 CA ASN A 132 -19.145 33.828 55.929 1.00 0.00 C ATOM 948 C ASN A 132 -19.131 35.256 55.392 1.00 0.00 C ATOM 949 O ASN A 132 -19.009 36.191 56.195 1.00 0.00 O ATOM 950 CB ASN A 132 -20.586 33.382 56.140 1.00 0.00 C ATOM 951 CG ASN A 132 -21.288 33.366 54.787 1.00 0.00 C ATOM 952 OD1 ASN A 132 -21.134 32.403 54.024 1.00 0.00 O ATOM 953 ND2 ASN A 132 -21.919 34.485 54.465 1.00 0.00 N ATOM 954 N ASN A 133 -18.778 35.329 54.116 1.00 0.00 N ATOM 955 CA ASN A 133 -18.675 36.583 53.344 1.00 0.00 C ATOM 956 C ASN A 133 -17.342 37.314 53.455 1.00 0.00 C ATOM 957 O ASN A 133 -17.308 38.535 53.257 1.00 0.00 O ATOM 958 CB ASN A 133 -19.832 37.549 53.595 1.00 0.00 C ATOM 959 CG ASN A 133 -20.834 37.450 52.452 1.00 0.00 C ATOM 960 OD1 ASN A 133 -21.906 36.849 52.606 1.00 0.00 O ATOM 961 ND2 ASN A 133 -20.538 38.208 51.410 1.00 0.00 N ATOM 962 N SER A 134 -16.384 36.645 54.080 1.00 0.00 N ATOM 963 CA SER A 134 -15.014 37.180 54.182 1.00 0.00 C ATOM 964 C SER A 134 -14.407 37.551 52.829 1.00 0.00 C ATOM 965 O SER A 134 -14.514 36.787 51.861 1.00 0.00 O ATOM 966 CB SER A 134 -14.087 36.214 54.917 1.00 0.00 C ATOM 967 OG SER A 134 -14.505 36.101 56.273 1.00 0.00 O ATOM 968 N PRO A 135 -13.912 38.781 52.776 1.00 0.00 N ATOM 969 CA PRO A 135 -13.318 39.420 51.581 1.00 0.00 C ATOM 970 C PRO A 135 -12.079 38.717 51.032 1.00 0.00 C ATOM 971 O PRO A 135 -11.043 38.656 51.707 1.00 0.00 O ATOM 972 CB PRO A 135 -12.959 40.840 52.012 1.00 0.00 C ATOM 973 CG PRO A 135 -12.845 40.765 53.525 1.00 0.00 C ATOM 974 CD PRO A 135 -13.882 39.721 53.915 1.00 0.00 C ATOM 975 N CYS A 136 -12.313 37.952 49.976 1.00 0.00 N ATOM 976 CA CYS A 136 -11.242 37.235 49.268 1.00 0.00 C ATOM 977 C CYS A 136 -11.223 37.526 47.767 1.00 0.00 C ATOM 978 O CYS A 136 -12.279 37.742 47.162 1.00 0.00 O ATOM 979 CB CYS A 136 -11.396 35.730 49.465 1.00 0.00 C ATOM 980 SG CYS A 136 -11.495 35.133 51.168 1.00 0.00 S ATOM 981 N TYR A 137 -10.052 37.347 47.175 1.00 0.00 N ATOM 982 CA TYR A 137 -9.815 37.512 45.730 1.00 0.00 C ATOM 983 C TYR A 137 -9.212 36.265 45.089 1.00 0.00 C ATOM 984 O TYR A 137 -8.407 35.571 45.721 1.00 0.00 O ATOM 985 CB TYR A 137 -8.865 38.683 45.459 1.00 0.00 C ATOM 986 CG TYR A 137 -9.557 40.056 45.510 1.00 0.00 C ATOM 987 CD1 TYR A 137 -10.074 40.605 44.347 1.00 0.00 C ATOM 988 CD2 TYR A 137 -9.622 40.766 46.698 1.00 0.00 C ATOM 989 CE1 TYR A 137 -10.696 41.858 44.373 1.00 0.00 C ATOM 990 CE2 TYR A 137 -10.242 42.021 46.735 1.00 0.00 C ATOM 991 CZ TYR A 137 -10.780 42.563 45.571 1.00 0.00 C ATOM 992 OH TYR A 137 -11.430 43.779 45.611 1.00 0.00 O ATOM 993 N ILE A 138 -9.700 35.923 43.908 1.00 0.00 N ATOM 994 CA ILE A 138 -9.100 34.822 43.144 1.00 0.00 C ATOM 995 C ILE A 138 -8.389 35.341 41.899 1.00 0.00 C ATOM 996 O ILE A 138 -8.832 36.343 41.327 1.00 0.00 O ATOM 997 CB ILE A 138 -10.123 33.753 42.750 1.00 0.00 C ATOM 998 CG1 ILE A 138 -9.445 32.544 42.102 1.00 0.00 C ATOM 999 CG2 ILE A 138 -11.238 34.310 41.867 1.00 0.00 C ATOM 1000 CD1 ILE A 138 -10.443 31.494 41.622 1.00 0.00 C ATOM 1001 N THR A 139 -7.114 35.011 41.842 1.00 0.00 N ATOM 1002 CA THR A 139 -6.277 35.404 40.710 1.00 0.00 C ATOM 1003 C THR A 139 -5.812 34.211 39.884 1.00 0.00 C ATOM 1004 O THR A 139 -5.716 33.093 40.404 1.00 0.00 O ATOM 1005 CB THR A 139 -5.072 36.182 41.218 1.00 0.00 C ATOM 1006 OG1 THR A 139 -4.374 35.362 42.147 1.00 0.00 O ATOM 1007 CG2 THR A 139 -5.511 37.461 41.920 1.00 0.00 C ATOM 1008 N GLY A 140 -5.615 34.462 38.601 1.00 0.00 N ATOM 1009 CA GLY A 140 -5.155 33.431 37.662 1.00 0.00 C ATOM 1010 C GLY A 140 -5.379 33.778 36.191 1.00 0.00 C ATOM 1011 O GLY A 140 -5.990 34.803 35.863 1.00 0.00 O ATOM 1012 N TRP A 141 -4.773 32.956 35.350 1.00 0.00 N ATOM 1013 CA TRP A 141 -4.811 33.096 33.889 1.00 0.00 C ATOM 1014 C TRP A 141 -5.777 32.114 33.240 1.00 0.00 C ATOM 1015 O TRP A 141 -5.793 32.013 32.007 1.00 0.00 O ATOM 1016 CB TRP A 141 -3.429 32.838 33.294 1.00 0.00 C ATOM 1017 CG TRP A 141 -2.430 33.971 33.570 1.00 0.00 C ATOM 1018 CD1 TRP A 141 -2.278 35.138 32.920 1.00 0.00 C ATOM 1019 CD2 TRP A 141 -1.455 33.983 34.566 1.00 0.00 C ATOM 1020 NE1 TRP A 141 -1.248 35.869 33.466 1.00 0.00 N ATOM 1021 CE2 TRP A 141 -0.750 35.204 34.435 1.00 0.00 C ATOM 1022 CE3 TRP A 141 -1.126 33.052 35.538 1.00 0.00 C ATOM 1023 CZ2 TRP A 141 0.293 35.567 35.270 1.00 0.00 C ATOM 1024 CZ3 TRP A 141 -0.064 33.409 36.380 1.00 0.00 C ATOM 1025 CH2 TRP A 141 0.621 34.625 36.252 1.00 0.00 C ATOM 1026 N GLY A 142 -6.779 31.735 34.017 1.00 0.00 N ATOM 1027 CA GLY A 142 -7.784 30.763 33.568 1.00 0.00 C ATOM 1028 C GLY A 142 -8.843 31.355 32.643 1.00 0.00 C ATOM 1029 O GLY A 142 -8.700 32.498 32.188 1.00 0.00 O ATOM 1030 N LEU A 143 -9.637 30.436 32.109 1.00 0.00 N ATOM 1031 CA LEU A 143 -10.697 30.753 31.141 1.00 0.00 C ATOM 1032 C LEU A 143 -11.613 31.878 31.621 1.00 0.00 C ATOM 1033 O LEU A 143 -11.967 31.935 32.805 1.00 0.00 O ATOM 1034 CB LEU A 143 -11.571 29.541 30.814 1.00 0.00 C ATOM 1035 CG LEU A 143 -10.835 28.270 30.389 1.00 0.00 C ATOM 1036 CD1 LEU A 143 -11.830 27.172 30.022 1.00 0.00 C ATOM 1037 CD2 LEU A 143 -9.834 28.487 29.260 1.00 0.00 C ATOM 1038 N THR A 144 -11.706 32.897 30.794 1.00 0.00 N ATOM 1039 CA THR A 144 -12.560 34.051 31.096 1.00 0.00 C ATOM 1040 C THR A 144 -14.045 33.737 30.932 1.00 0.00 C ATOM 1041 O THR A 144 -14.890 34.595 31.217 1.00 0.00 O ATOM 1042 CB THR A 144 -12.174 35.219 30.201 1.00 0.00 C ATOM 1043 OG1 THR A 144 -12.340 34.817 28.846 1.00 0.00 O ATOM 1044 CG2 THR A 144 -10.724 35.641 30.430 1.00 0.00 C ATOM 1045 N ARG A 145 -14.282 32.694 30.156 1.00 0.00 N ATOM 1046 CA ARG A 145 -15.615 32.127 29.884 1.00 0.00 C ATOM 1047 C ARG A 145 -15.609 30.604 29.986 1.00 0.00 C ATOM 1048 O ARG A 145 -14.556 29.978 29.821 1.00 0.00 O ATOM 1049 CB ARG A 145 -16.055 32.486 28.463 1.00 0.00 C ATOM 1050 CG ARG A 145 -16.693 33.867 28.307 1.00 0.00 C ATOM 1051 CD ARG A 145 -18.158 33.892 28.746 1.00 0.00 C ATOM 1052 NE ARG A 145 -18.952 34.629 27.748 1.00 0.00 N ATOM 1053 CZ ARG A 145 -20.077 34.170 27.212 1.00 0.00 C ATOM 1054 NH1 ARG A 145 -20.677 34.891 26.277 1.00 0.00 N ATOM 1055 NH2 ARG A 145 -20.809 33.310 27.904 1.00 0.00 N ATOM 1056 N THR A 147 -16.759 30.046 30.324 1.00 0.00 N ATOM 1057 CA THR A 147 -16.934 28.590 30.312 1.00 0.00 C ATOM 1058 C THR A 147 -16.792 28.065 28.885 1.00 0.00 C ATOM 1059 O THR A 147 -17.320 28.702 27.963 1.00 0.00 O ATOM 1060 CB THR A 147 -18.303 28.216 30.881 1.00 0.00 C ATOM 1061 OG1 THR A 147 -18.380 28.641 32.241 1.00 0.00 O ATOM 1062 CG2 THR A 147 -18.568 26.714 30.814 1.00 0.00 C ATOM 1063 N ASN A 148 -15.754 27.251 28.722 1.00 0.00 N ATOM 1064 CA ASN A 148 -15.318 26.674 27.438 1.00 0.00 C ATOM 1065 C ASN A 148 -14.670 27.716 26.533 1.00 0.00 C ATOM 1066 O ASN A 148 -14.884 27.697 25.315 1.00 0.00 O ATOM 1067 CB ASN A 148 -16.439 25.950 26.689 1.00 0.00 C ATOM 1068 CG ASN A 148 -16.799 24.649 27.402 1.00 0.00 C ATOM 1069 OD1 ASN A 148 -15.918 23.978 27.954 1.00 0.00 O ATOM 1070 ND2 ASN A 148 -18.096 24.431 27.533 1.00 0.00 N ATOM 1071 N GLY A 149 -14.229 28.776 27.191 1.00 0.00 N ATOM 1072 CA GLY A 149 -13.536 29.894 26.535 1.00 0.00 C ATOM 1073 C GLY A 149 -12.025 29.690 26.455 1.00 0.00 C ATOM 1074 O GLY A 149 -11.562 28.600 26.093 1.00 0.00 O ATOM 1075 N GLN A 150 -11.311 30.802 26.501 1.00 0.00 N ATOM 1076 CA GLN A 150 -9.846 30.800 26.405 1.00 0.00 C ATOM 1077 C GLN A 150 -9.141 31.495 27.567 1.00 0.00 C ATOM 1078 O GLN A 150 -9.784 32.197 28.360 1.00 0.00 O ATOM 1079 CB GLN A 150 -9.418 31.430 25.084 1.00 0.00 C ATOM 1080 CG GLN A 150 -10.023 32.820 24.902 1.00 0.00 C ATOM 1081 CD GLN A 150 -9.620 33.374 23.538 1.00 0.00 C ATOM 1082 OE1 GLN A 150 -10.003 34.499 23.192 1.00 0.00 O ATOM 1083 NE2 GLN A 150 -9.110 32.480 22.706 1.00 0.00 N ATOM 1084 N LEU A 151 -7.905 31.056 27.775 1.00 0.00 N ATOM 1085 CA LEU A 151 -7.020 31.577 28.822 1.00 0.00 C ATOM 1086 C LEU A 151 -6.785 33.074 28.665 1.00 0.00 C ATOM 1087 O LEU A 151 -6.637 33.576 27.543 1.00 0.00 O ATOM 1088 CB LEU A 151 -5.657 30.882 28.780 1.00 0.00 C ATOM 1089 CG LEU A 151 -5.713 29.382 29.066 1.00 0.00 C ATOM 1090 CD1 LEU A 151 -4.358 28.717 28.826 1.00 0.00 C ATOM 1091 CD2 LEU A 151 -6.248 29.071 30.463 1.00 0.00 C ATOM 1092 N ALA A 152 -6.732 33.746 29.796 1.00 0.00 N ATOM 1093 CA ALA A 152 -6.444 35.182 29.817 1.00 0.00 C ATOM 1094 C ALA A 152 -4.960 35.453 29.586 1.00 0.00 C ATOM 1095 O ALA A 152 -4.144 34.569 29.876 1.00 0.00 O ATOM 1096 CB ALA A 152 -6.845 35.752 31.172 1.00 0.00 C ATOM 1097 N GLN A 153 -4.692 36.389 28.692 1.00 0.00 N ATOM 1098 CA GLN A 153 -3.301 36.782 28.434 1.00 0.00 C ATOM 1099 C GLN A 153 -2.648 37.403 29.663 1.00 0.00 C ATOM 1100 O GLN A 153 -1.545 37.004 30.056 1.00 0.00 O ATOM 1101 CB GLN A 153 -3.185 37.753 27.262 1.00 0.00 C ATOM 1102 CG GLN A 153 -3.540 37.110 25.925 1.00 0.00 C ATOM 1103 CD GLN A 153 -3.117 38.060 24.809 1.00 0.00 C ATOM 1104 OE1 GLN A 153 -3.626 37.955 23.685 1.00 0.00 O ATOM 1105 NE2 GLN A 153 -1.959 38.666 25.037 1.00 0.00 N ATOM 1106 N THR A 154 -3.396 38.293 30.291 1.00 0.00 N ATOM 1107 CA THR A 154 -2.954 38.985 31.507 1.00 0.00 C ATOM 1108 C THR A 154 -3.647 38.451 32.755 1.00 0.00 C ATOM 1109 O THR A 154 -4.838 38.121 32.696 1.00 0.00 O ATOM 1110 CB THR A 154 -3.182 40.491 31.405 1.00 0.00 C ATOM 1111 OG1 THR A 154 -4.580 40.757 31.339 1.00 0.00 O ATOM 1112 CG2 THR A 154 -2.472 41.108 30.202 1.00 0.00 C ATOM 1113 N LEU A 155 -2.976 38.659 33.876 1.00 0.00 N ATOM 1114 CA LEU A 155 -3.413 38.165 35.190 1.00 0.00 C ATOM 1115 C LEU A 155 -4.712 38.812 35.665 1.00 0.00 C ATOM 1116 O LEU A 155 -4.839 40.042 35.591 1.00 0.00 O ATOM 1117 CB LEU A 155 -2.302 38.390 36.218 1.00 0.00 C ATOM 1118 CG LEU A 155 -2.572 37.701 37.557 1.00 0.00 C ATOM 1119 CD1 LEU A 155 -2.754 36.195 37.398 1.00 0.00 C ATOM 1120 CD2 LEU A 155 -1.488 38.017 38.586 1.00 0.00 C ATOM 1121 N GLN A 156 -5.747 37.984 35.630 1.00 0.00 N ATOM 1122 CA GLN A 156 -7.092 38.375 36.069 1.00 0.00 C ATOM 1123 C GLN A 156 -7.326 38.143 37.559 1.00 0.00 C ATOM 1124 O GLN A 156 -6.653 37.300 38.164 1.00 0.00 O ATOM 1125 CB GLN A 156 -8.144 37.583 35.294 1.00 0.00 C ATOM 1126 CG GLN A 156 -8.018 37.749 33.782 1.00 0.00 C ATOM 1127 CD GLN A 156 -8.231 39.209 33.392 1.00 0.00 C ATOM 1128 OE1 GLN A 156 -9.322 39.757 33.601 1.00 0.00 O ATOM 1129 NE2 GLN A 156 -7.186 39.804 32.830 1.00 0.00 N ATOM 1130 N GLN A 157 -8.056 39.081 38.147 1.00 0.00 N ATOM 1131 CA GLN A 157 -8.508 39.012 39.544 1.00 0.00 C ATOM 1132 C GLN A 157 -10.013 39.234 39.700 1.00 0.00 C ATOM 1133 O GLN A 157 -10.602 40.057 38.988 1.00 0.00 O ATOM 1134 CB GLN A 157 -7.744 39.987 40.441 1.00 0.00 C ATOM 1135 CG GLN A 157 -7.867 41.440 39.989 1.00 0.00 C ATOM 1136 CD GLN A 157 -7.321 42.358 41.080 1.00 0.00 C ATOM 1137 OE1 GLN A 157 -6.155 42.769 41.020 1.00 0.00 O ATOM 1138 NE2 GLN A 157 -8.257 42.916 41.833 1.00 0.00 N ATOM 1139 N ALA A 158 -10.601 38.511 40.645 1.00 0.00 N ATOM 1140 CA ALA A 158 -12.043 38.602 40.929 1.00 0.00 C ATOM 1141 C ALA A 158 -12.394 38.527 42.413 1.00 0.00 C ATOM 1142 O ALA A 158 -12.019 37.559 43.088 1.00 0.00 O ATOM 1143 CB ALA A 158 -12.803 37.511 40.180 1.00 0.00 C ATOM 1144 N TYR A 159 -13.335 39.385 42.790 1.00 0.00 N ATOM 1145 CA TYR A 159 -13.852 39.457 44.162 1.00 0.00 C ATOM 1146 C TYR A 159 -14.794 38.293 44.451 1.00 0.00 C ATOM 1147 O TYR A 159 -15.812 38.143 43.760 1.00 0.00 O ATOM 1148 CB TYR A 159 -14.578 40.784 44.405 1.00 0.00 C ATOM 1149 CG TYR A 159 -14.959 40.967 45.885 1.00 0.00 C ATOM 1150 CD1 TYR A 159 -13.967 40.982 46.852 1.00 0.00 C ATOM 1151 CD2 TYR A 159 -16.285 41.138 46.253 1.00 0.00 C ATOM 1152 CE1 TYR A 159 -14.296 41.152 48.201 1.00 0.00 C ATOM 1153 CE2 TYR A 159 -16.625 41.308 47.602 1.00 0.00 C ATOM 1154 CZ TYR A 159 -15.627 41.314 48.576 1.00 0.00 C ATOM 1155 OH TYR A 159 -15.967 41.288 49.913 1.00 0.00 O ATOM 1156 N LEU A 160 -14.184 37.301 45.076 1.00 0.00 N ATOM 1157 CA LEU A 160 -14.864 36.065 45.495 1.00 0.00 C ATOM 1158 C LEU A 160 -14.951 35.929 47.015 1.00 0.00 C ATOM 1159 O LEU A 160 -14.050 35.333 47.615 1.00 0.00 O ATOM 1160 CB LEU A 160 -14.077 34.868 44.959 1.00 0.00 C ATOM 1161 CG LEU A 160 -14.835 34.066 43.901 1.00 0.00 C ATOM 1162 CD1 LEU A 160 -15.290 34.920 42.721 1.00 0.00 C ATOM 1163 CD2 LEU A 160 -14.049 32.839 43.444 1.00 0.00 C ATOM 1164 N PRO A 161 -15.930 36.581 47.638 1.00 0.00 N ATOM 1165 CA PRO A 161 -16.243 36.390 49.070 1.00 0.00 C ATOM 1166 C PRO A 161 -16.636 34.956 49.423 1.00 0.00 C ATOM 1167 O PRO A 161 -17.361 34.303 48.662 1.00 0.00 O ATOM 1168 CB PRO A 161 -17.384 37.353 49.373 1.00 0.00 C ATOM 1169 CG PRO A 161 -18.091 37.519 48.041 1.00 0.00 C ATOM 1170 CD PRO A 161 -16.976 37.415 47.006 1.00 0.00 C ATOM 1171 N THR A 162 -16.419 34.627 50.685 1.00 0.00 N ATOM 1172 CA THR A 162 -16.590 33.253 51.175 1.00 0.00 C ATOM 1173 C THR A 162 -18.014 32.841 51.535 1.00 0.00 C ATOM 1174 O THR A 162 -18.892 33.685 51.750 1.00 0.00 O ATOM 1175 CB THR A 162 -15.736 33.019 52.412 1.00 0.00 C ATOM 1176 OG1 THR A 162 -16.171 33.916 53.423 1.00 0.00 O ATOM 1177 CG2 THR A 162 -14.247 33.211 52.145 1.00 0.00 C ATOM 1178 N VAL A 163 -18.232 31.561 51.294 1.00 0.00 N ATOM 1179 CA VAL A 163 -19.434 30.814 51.672 1.00 0.00 C ATOM 1180 C VAL A 163 -19.033 29.702 52.637 1.00 0.00 C ATOM 1181 O VAL A 163 -18.113 28.941 52.307 1.00 0.00 O ATOM 1182 CB VAL A 163 -20.049 30.173 50.427 1.00 0.00 C ATOM 1183 CG1 VAL A 163 -21.308 29.372 50.756 1.00 0.00 C ATOM 1184 CG2 VAL A 163 -20.305 31.187 49.315 1.00 0.00 C ATOM 1185 N ASP A 164 -19.413 29.866 53.903 1.00 0.00 N ATOM 1186 CA ASP A 164 -19.037 28.871 54.920 1.00 0.00 C ATOM 1187 C ASP A 164 -19.526 27.456 54.626 1.00 0.00 C ATOM 1188 O ASP A 164 -20.580 27.310 53.993 1.00 0.00 O ATOM 1189 CB ASP A 164 -19.372 29.291 56.355 1.00 0.00 C ATOM 1190 CG ASP A 164 -20.873 29.484 56.574 1.00 0.00 C ATOM 1191 OD1 ASP A 164 -21.690 28.767 55.985 1.00 0.00 O ATOM 1192 OD2 ASP A 164 -21.241 30.296 57.431 1.00 0.00 O ATOM 1193 N TYR A 165 -19.024 26.556 55.452 1.00 0.00 N ATOM 1194 CA TYR A 165 -19.282 25.116 55.330 1.00 0.00 C ATOM 1195 C TYR A 165 -20.763 24.779 55.446 1.00 0.00 C ATOM 1196 O TYR A 165 -21.326 24.280 54.464 1.00 0.00 O ATOM 1197 CB TYR A 165 -18.498 24.330 56.382 1.00 0.00 C ATOM 1198 CG TYR A 165 -18.615 22.822 56.114 1.00 0.00 C ATOM 1199 CD1 TYR A 165 -18.267 22.325 54.869 1.00 0.00 C ATOM 1200 CD2 TYR A 165 -19.078 21.963 57.100 1.00 0.00 C ATOM 1201 CE1 TYR A 165 -18.382 20.960 54.599 1.00 0.00 C ATOM 1202 CE2 TYR A 165 -19.192 20.590 56.840 1.00 0.00 C ATOM 1203 CZ TYR A 165 -18.844 20.094 55.584 1.00 0.00 C ATOM 1204 OH TYR A 165 -18.966 18.748 55.306 1.00 0.00 O ATOM 1205 N ALA A 166 -21.383 25.507 56.362 1.00 0.00 N ATOM 1206 CA ALA A 166 -22.796 25.326 56.722 1.00 0.00 C ATOM 1207 C ALA A 166 -23.723 25.504 55.526 1.00 0.00 C ATOM 1208 O ALA A 166 -24.289 24.509 55.050 1.00 0.00 O ATOM 1209 CB ALA A 166 -23.185 26.323 57.811 1.00 0.00 C ATOM 1210 N ILE A 167 -23.349 26.521 54.779 1.00 0.00 N ATOM 1211 CA ILE A 167 -24.113 26.903 53.593 1.00 0.00 C ATOM 1212 C ILE A 167 -23.649 26.174 52.339 1.00 0.00 C ATOM 1213 O ILE A 167 -24.479 25.552 51.670 1.00 0.00 O ATOM 1214 CB ILE A 167 -24.045 28.413 53.374 1.00 0.00 C ATOM 1215 CG1 ILE A 167 -24.602 29.188 54.565 1.00 0.00 C ATOM 1216 CG2 ILE A 167 -24.725 28.836 52.075 1.00 0.00 C ATOM 1217 CD1 ILE A 167 -24.519 30.697 54.347 1.00 0.00 C ATOM 1218 N CYS A 168 -22.360 25.894 52.298 1.00 0.00 N ATOM 1219 CA CYS A 168 -21.793 25.293 51.084 1.00 0.00 C ATOM 1220 C CYS A 168 -22.082 23.799 50.989 1.00 0.00 C ATOM 1221 O CYS A 168 -22.354 23.288 49.895 1.00 0.00 O ATOM 1222 CB CYS A 168 -20.292 25.542 50.998 1.00 0.00 C ATOM 1223 SG CYS A 168 -19.571 25.199 49.380 1.00 0.00 S ATOM 1224 N SER A 169 -22.463 23.271 52.131 1.00 0.00 N ATOM 1225 CA SER A 169 -22.803 21.852 52.207 1.00 0.00 C ATOM 1226 C SER A 169 -24.308 21.642 52.122 1.00 0.00 C ATOM 1227 O SER A 169 -24.802 20.530 52.340 1.00 0.00 O ATOM 1228 CB SER A 169 -22.261 21.222 53.484 1.00 0.00 C ATOM 1229 OG SER A 169 -22.870 21.865 54.595 1.00 0.00 O ATOM 1230 N SER A 170 -24.996 22.713 51.761 1.00 0.00 N ATOM 1231 CA SER A 170 -26.441 22.615 51.524 1.00 0.00 C ATOM 1232 C SER A 170 -26.720 22.000 50.159 1.00 0.00 C ATOM 1233 O SER A 170 -25.831 22.012 49.298 1.00 0.00 O ATOM 1234 CB SER A 170 -27.125 23.978 51.596 1.00 0.00 C ATOM 1235 OG SER A 170 -26.910 24.550 52.882 1.00 0.00 O ATOM 1236 N SER A 171A -27.709 21.128 50.167 1.00 0.00 N ATOM 1237 CA SER A 171A -28.184 20.450 48.955 1.00 0.00 C ATOM 1238 C SER A 171A -28.496 21.434 47.830 1.00 0.00 C ATOM 1239 O SER A 171A -28.281 21.121 46.652 1.00 0.00 O ATOM 1240 CB SER A 171A -29.428 19.631 49.277 1.00 0.00 C ATOM 1241 OG SER A 171A -30.432 20.507 49.774 1.00 0.00 O ATOM 1242 N SER A 171B -28.775 22.662 48.232 1.00 0.00 N ATOM 1243 CA SER A 171B -29.036 23.770 47.306 1.00 0.00 C ATOM 1244 C SER A 171B -27.742 24.304 46.702 1.00 0.00 C ATOM 1245 O SER A 171B -27.732 24.802 45.569 1.00 0.00 O ATOM 1246 CB SER A 171B -29.747 24.903 48.039 1.00 0.00 C ATOM 1247 OG SER A 171B -29.990 25.963 47.120 1.00 0.00 O ATOM 1248 N TYR A 171 -26.658 23.946 47.373 1.00 0.00 N ATOM 1249 CA TYR A 171 -25.294 24.307 46.957 1.00 0.00 C ATOM 1250 C TYR A 171 -24.521 23.089 46.448 1.00 0.00 C ATOM 1251 O TYR A 171 -25.109 22.291 45.708 1.00 0.00 O ATOM 1252 CB TYR A 171 -24.523 25.022 48.073 1.00 0.00 C ATOM 1253 CG TYR A 171 -24.910 26.504 48.243 1.00 0.00 C ATOM 1254 CD1 TYR A 171 -26.158 26.860 48.734 1.00 0.00 C ATOM 1255 CD2 TYR A 171 -23.984 27.491 47.938 1.00 0.00 C ATOM 1256 CE1 TYR A 171 -26.499 28.208 48.892 1.00 0.00 C ATOM 1257 CE2 TYR A 171 -24.315 28.843 48.095 1.00 0.00 C ATOM 1258 CZ TYR A 171 -25.575 29.201 48.570 1.00 0.00 C ATOM 1259 OH TYR A 171 -25.995 30.511 48.468 1.00 0.00 O ATOM 1260 N TRP A 172 -23.501 22.709 47.203 1.00 0.00 N ATOM 1261 CA TRP A 172 -22.639 21.578 46.808 1.00 0.00 C ATOM 1262 C TRP A 172 -22.999 20.231 47.429 1.00 0.00 C ATOM 1263 O TRP A 172 -22.483 19.192 46.994 1.00 0.00 O ATOM 1264 CB TRP A 172 -21.160 21.869 47.058 1.00 0.00 C ATOM 1265 CG TRP A 172 -20.529 22.687 45.922 1.00 0.00 C ATOM 1266 CD1 TRP A 172 -20.212 23.996 45.869 1.00 0.00 C ATOM 1267 CD2 TRP A 172 -20.134 22.170 44.689 1.00 0.00 C ATOM 1268 NE1 TRP A 172 -19.646 24.304 44.647 1.00 0.00 N ATOM 1269 CE2 TRP A 172 -19.592 23.243 43.944 1.00 0.00 C ATOM 1270 CE3 TRP A 172 -20.199 20.884 44.174 1.00 0.00 C ATOM 1271 CZ2 TRP A 172 -19.092 23.096 42.661 1.00 0.00 C ATOM 1272 CZ3 TRP A 172 -19.700 20.728 42.875 1.00 0.00 C ATOM 1273 CH2 TRP A 172 -19.164 21.797 42.144 1.00 0.00 C ATOM 1274 N GLY A 173 -23.670 20.293 48.564 1.00 0.00 N ATOM 1275 CA GLY A 173 -24.036 19.064 49.276 1.00 0.00 C ATOM 1276 C GLY A 173 -22.850 18.467 50.029 1.00 0.00 C ATOM 1277 O GLY A 173 -21.946 19.208 50.431 1.00 0.00 O ATOM 1278 N SER A 174 -22.686 17.173 49.871 1.00 0.00 N ATOM 1279 CA SER A 174 -21.626 16.457 50.588 1.00 0.00 C ATOM 1280 C SER A 174 -20.326 16.376 49.797 1.00 0.00 C ATOM 1281 O SER A 174 -19.444 15.587 50.154 1.00 0.00 O ATOM 1282 CB SER A 174 -22.091 15.045 50.920 1.00 0.00 C ATOM 1283 OG SER A 174 -22.331 14.354 49.700 1.00 0.00 O ATOM 1284 N THR A 175 -20.362 16.958 48.611 1.00 0.00 N ATOM 1285 CA THR A 175 -19.186 16.976 47.726 1.00 0.00 C ATOM 1286 C THR A 175 -18.035 17.767 48.338 1.00 0.00 C ATOM 1287 O THR A 175 -16.885 17.308 48.330 1.00 0.00 O ATOM 1288 CB THR A 175 -19.561 17.575 46.372 1.00 0.00 C ATOM 1289 OG1 THR A 175 -20.599 16.791 45.795 1.00 0.00 O ATOM 1290 CG2 THR A 175 -18.377 17.634 45.407 1.00 0.00 C ATOM 1291 N VAL A 176 -18.442 18.695 49.181 1.00 0.00 N ATOM 1292 CA VAL A 176 -17.505 19.585 49.870 1.00 0.00 C ATOM 1293 C VAL A 176 -17.271 19.175 51.321 1.00 0.00 C ATOM 1294 O VAL A 176 -18.183 18.620 51.948 1.00 0.00 O ATOM 1295 CB VAL A 176 -17.981 21.037 49.764 1.00 0.00 C ATOM 1296 CG1 VAL A 176 -19.464 21.199 50.076 1.00 0.00 C ATOM 1297 CG2 VAL A 176 -17.115 22.028 50.538 1.00 0.00 C ATOM 1298 N LYS A 177 -15.993 18.978 51.596 1.00 0.00 N ATOM 1299 CA LYS A 177 -15.473 18.607 52.917 1.00 0.00 C ATOM 1300 C LYS A 177 -15.038 19.845 53.695 1.00 0.00 C ATOM 1301 O LYS A 177 -14.907 20.922 53.102 1.00 0.00 O ATOM 1302 CB LYS A 177 -14.252 17.709 52.735 1.00 0.00 C ATOM 1303 CG LYS A 177 -14.542 16.524 51.818 1.00 0.00 C ATOM 1304 CD LYS A 177 -15.591 15.578 52.396 1.00 0.00 C ATOM 1305 CE LYS A 177 -16.040 14.546 51.366 1.00 0.00 C ATOM 1306 NZ LYS A 177 -16.636 15.234 50.212 1.00 0.00 N ATOM 1307 N ASN A 178 -15.072 19.729 55.015 1.00 0.00 N ATOM 1308 CA ASN A 178 -14.702 20.817 55.937 1.00 0.00 C ATOM 1309 C ASN A 178 -13.307 21.390 55.681 1.00 0.00 C ATOM 1310 O ASN A 178 -13.135 22.616 55.701 1.00 0.00 O ATOM 1311 CB ASN A 178 -14.808 20.338 57.383 1.00 0.00 C ATOM 1312 CG ASN A 178 -14.492 21.508 58.309 1.00 0.00 C ATOM 1313 OD1 ASN A 178 -13.609 21.401 59.170 1.00 0.00 O ATOM 1314 ND2 ASN A 178 -14.977 22.666 57.893 1.00 0.00 N ATOM 1315 N SER A 179 -12.540 20.574 54.978 1.00 0.00 N ATOM 1316 CA SER A 179 -11.167 20.884 54.561 1.00 0.00 C ATOM 1317 C SER A 179 -11.133 21.759 53.311 1.00 0.00 C ATOM 1318 O SER A 179 -10.144 21.731 52.567 1.00 0.00 O ATOM 1319 CB SER A 179 -10.436 19.584 54.245 1.00 0.00 C ATOM 1320 OG SER A 179 -11.085 18.961 53.141 1.00 0.00 O ATOM 1321 N MET A 180 -12.318 22.207 52.929 1.00 0.00 N ATOM 1322 CA MET A 180 -12.475 23.077 51.755 1.00 0.00 C ATOM 1323 C MET A 180 -13.059 24.448 52.090 1.00 0.00 C ATOM 1324 O MET A 180 -13.528 24.660 53.215 1.00 0.00 O ATOM 1325 CB MET A 180 -13.366 22.412 50.707 1.00 0.00 C ATOM 1326 CG MET A 180 -12.834 21.056 50.249 1.00 0.00 C ATOM 1327 SD MET A 180 -13.867 20.201 49.039 1.00 0.00 S ATOM 1328 CE MET A 180 -12.923 18.674 48.881 1.00 0.00 C ATOM 1329 N VAL A 181 -12.736 25.405 51.232 1.00 0.00 N ATOM 1330 CA VAL A 181 -13.268 26.775 51.309 1.00 0.00 C ATOM 1331 C VAL A 181 -14.093 27.086 50.063 1.00 0.00 C ATOM 1332 O VAL A 181 -13.805 26.522 49.001 1.00 0.00 O ATOM 1333 CB VAL A 181 -12.119 27.786 51.384 1.00 0.00 C ATOM 1334 CG1 VAL A 181 -12.614 29.218 51.584 1.00 0.00 C ATOM 1335 CG2 VAL A 181 -11.093 27.421 52.450 1.00 0.00 C ATOM 1336 N CYS A 182 -15.283 27.623 50.274 1.00 0.00 N ATOM 1337 CA CYS A 182 -16.116 28.036 49.141 1.00 0.00 C ATOM 1338 C CYS A 182 -16.202 29.554 49.027 1.00 0.00 C ATOM 1339 O CYS A 182 -16.042 30.238 50.044 1.00 0.00 O ATOM 1340 CB CYS A 182 -17.521 27.461 49.260 1.00 0.00 C ATOM 1341 SG CYS A 182 -17.603 25.680 49.529 1.00 0.00 S ATOM 1342 N ALA A 183 -15.972 30.009 47.807 1.00 0.00 N ATOM 1343 CA ALA A 183 -16.038 31.438 47.483 1.00 0.00 C ATOM 1344 C ALA A 183 -16.749 31.739 46.166 1.00 0.00 C ATOM 1345 O ALA A 183 -16.548 31.036 45.167 1.00 0.00 O ATOM 1346 CB ALA A 183 -14.641 32.053 47.472 1.00 0.00 C ATOM 1347 N GLY A 184 -17.661 32.698 46.239 1.00 0.00 N ATOM 1348 CA GLY A 184 -18.428 33.162 45.073 1.00 0.00 C ATOM 1349 C GLY A 184 -19.789 32.482 44.942 1.00 0.00 C ATOM 1350 O GLY A 184 -20.593 32.517 45.883 1.00 0.00 O ATOM 1351 N GLY A 185 -20.115 32.128 43.711 1.00 0.00 N ATOM 1352 CA GLY A 185 -21.363 31.420 43.398 1.00 0.00 C ATOM 1353 C GLY A 185 -22.471 32.352 42.920 1.00 0.00 C ATOM 1354 O GLY A 185 -23.654 31.995 43.007 1.00 0.00 O ATOM 1355 N ASP A 186 -22.095 33.613 42.752 1.00 0.00 N ATOM 1356 CA ASP A 186 -23.022 34.658 42.284 1.00 0.00 C ATOM 1357 C ASP A 186 -23.513 34.430 40.856 1.00 0.00 C ATOM 1358 O ASP A 186 -24.315 35.216 40.338 1.00 0.00 O ATOM 1359 CB ASP A 186 -22.418 36.060 42.420 1.00 0.00 C ATOM 1360 CG ASP A 186 -21.202 36.261 41.511 1.00 0.00 C ATOM 1361 OD1 ASP A 186 -20.694 37.388 41.452 1.00 0.00 O ATOM 1362 OD2 ASP A 186 -20.615 35.278 41.042 1.00 0.00 O ATOM 1363 N GLY A 187 -22.781 33.573 40.173 1.00 0.00 N ATOM 1364 CA GLY A 187 -23.098 33.207 38.788 1.00 0.00 C ATOM 1365 C GLY A 187 -22.420 34.121 37.774 1.00 0.00 C ATOM 1366 O GLY A 187 -22.666 33.997 36.567 1.00 0.00 O ATOM 1367 N VAL A 188 -21.808 35.171 38.293 1.00 0.00 N ATOM 1368 CA VAL A 188 -21.107 36.134 37.432 1.00 0.00 C ATOM 1369 C VAL A 188 -19.592 35.969 37.487 1.00 0.00 C ATOM 1370 O VAL A 188 -18.954 35.699 36.461 1.00 0.00 O ATOM 1371 CB VAL A 188 -21.482 37.562 37.823 1.00 0.00 C ATOM 1372 CG1 VAL A 188 -20.667 38.606 37.060 1.00 0.00 C ATOM 1373 CG2 VAL A 188 -22.983 37.811 37.692 1.00 0.00 C ATOM 1374 N ARG A 188A -19.127 35.782 38.709 1.00 0.00 N ATOM 1375 CA ARG A 188A -17.697 35.653 39.001 1.00 0.00 C ATOM 1376 C ARG A 188A -17.326 34.281 39.553 1.00 0.00 C ATOM 1377 O ARG A 188A -17.993 33.786 40.471 1.00 0.00 O ATOM 1378 CB ARG A 188A -17.294 36.715 40.018 1.00 0.00 C ATOM 1379 CG ARG A 188A -17.497 38.129 39.484 1.00 0.00 C ATOM 1380 CD ARG A 188A -17.141 39.183 40.528 1.00 0.00 C ATOM 1381 NE ARG A 188A -18.101 39.137 41.639 1.00 0.00 N ATOM 1382 CZ ARG A 188A -18.520 40.232 42.254 1.00 0.00 C ATOM 1383 NH1 ARG A 188A -19.413 40.116 43.224 1.00 0.00 N ATOM 1384 NH2 ARG A 188A -17.758 41.315 42.212 1.00 0.00 N ATOM 1385 N SER A 189 -16.204 33.765 39.069 1.00 0.00 N ATOM 1386 CA SER A 189 -15.667 32.479 39.535 1.00 0.00 C ATOM 1387 C SER A 189 -14.255 32.200 39.034 1.00 0.00 C ATOM 1388 O SER A 189 -13.799 32.852 38.087 1.00 0.00 O ATOM 1389 CB SER A 189 -16.539 31.330 39.035 1.00 0.00 C ATOM 1390 OG SER A 189 -16.363 31.196 37.628 1.00 0.00 O ATOM 1391 N GLY A 190 -13.882 30.966 39.316 1.00 0.00 N ATOM 1392 CA GLY A 190 -12.648 30.346 38.829 1.00 0.00 C ATOM 1393 C GLY A 190 -12.992 29.379 37.702 1.00 0.00 C ATOM 1394 O GLY A 190 -14.180 29.102 37.496 1.00 0.00 O ATOM 1395 N CYS A 191 -12.034 29.175 36.816 1.00 0.00 N ATOM 1396 CA CYS A 191 -12.243 28.329 35.635 1.00 0.00 C ATOM 1397 C CYS A 191 -10.970 27.571 35.261 1.00 0.00 C ATOM 1398 O CYS A 191 -10.039 27.548 36.078 1.00 0.00 O ATOM 1399 CB CYS A 191 -12.684 29.247 34.494 1.00 0.00 C ATOM 1400 SG CYS A 191 -13.863 28.568 33.306 1.00 0.00 S ATOM 1401 N GLN A 192 -11.130 26.644 34.322 1.00 0.00 N ATOM 1402 CA GLN A 192 -10.012 25.856 33.784 1.00 0.00 C ATOM 1403 C GLN A 192 -8.750 26.675 33.523 1.00 0.00 C ATOM 1404 O GLN A 192 -8.804 27.692 32.822 1.00 0.00 O ATOM 1405 CB GLN A 192 -10.397 25.091 32.518 1.00 0.00 C ATOM 1406 CG GLN A 192 -11.297 23.884 32.784 1.00 0.00 C ATOM 1407 CD GLN A 192 -12.677 24.332 33.254 1.00 0.00 C ATOM 1408 OE1 GLN A 192 -13.237 25.276 32.683 1.00 0.00 O ATOM 1409 NE2 GLN A 192 -13.328 23.419 33.958 1.00 0.00 N ATOM 1410 N GLY A 193 -7.783 26.436 34.385 1.00 0.00 N ATOM 1411 CA GLY A 193 -6.474 27.089 34.302 1.00 0.00 C ATOM 1412 C GLY A 193 -6.078 27.771 35.606 1.00 0.00 C ATOM 1413 O GLY A 193 -4.928 28.208 35.746 1.00 0.00 O ATOM 1414 N ASP A 194 -7.101 28.152 36.356 1.00 0.00 N ATOM 1415 CA ASP A 194 -6.895 28.821 37.648 1.00 0.00 C ATOM 1416 C ASP A 194 -6.380 27.891 38.741 1.00 0.00 C ATOM 1417 O ASP A 194 -6.062 28.378 39.835 1.00 0.00 O ATOM 1418 CB ASP A 194 -8.175 29.500 38.130 1.00 0.00 C ATOM 1419 CG ASP A 194 -8.533 30.633 37.174 1.00 0.00 C ATOM 1420 OD1 ASP A 194 -7.627 31.352 36.737 1.00 0.00 O ATOM 1421 OD2 ASP A 194 -9.689 30.723 36.748 1.00 0.00 O ATOM 1422 N SER A 195 -6.651 26.604 38.533 1.00 0.00 N ATOM 1423 CA SER A 195 -6.289 25.523 39.474 1.00 0.00 C ATOM 1424 C SER A 195 -4.940 25.680 40.163 1.00 0.00 C ATOM 1425 O SER A 195 -3.922 25.926 39.513 1.00 0.00 O ATOM 1426 CB SER A 195 -6.335 24.137 38.837 1.00 0.00 C ATOM 1427 OG SER A 195 -7.669 23.561 38.722 1.00 0.00 O ATOM 1428 N GLY A 196 -4.936 25.352 41.434 1.00 0.00 N ATOM 1429 CA GLY A 196 -3.712 25.365 42.233 1.00 0.00 C ATOM 1430 C GLY A 196 -3.349 26.759 42.719 1.00 0.00 C ATOM 1431 O GLY A 196 -2.303 26.925 43.360 1.00 0.00 O ATOM 1432 N GLY A 197 -3.951 27.719 42.040 1.00 0.00 N ATOM 1433 CA GLY A 197 -3.742 29.138 42.337 1.00 0.00 C ATOM 1434 C GLY A 197 -4.634 29.659 43.459 1.00 0.00 C ATOM 1435 O GLY A 197 -5.291 28.872 44.152 1.00 0.00 O ATOM 1436 N PRO A 198 -4.295 30.867 43.856 1.00 0.00 N ATOM 1437 CA PRO A 198 -4.460 31.300 45.258 1.00 0.00 C ATOM 1438 C PRO A 198 -5.687 32.177 45.497 1.00 0.00 C ATOM 1439 O PRO A 198 -6.256 32.711 44.535 1.00 0.00 O ATOM 1440 CB PRO A 198 -3.198 32.083 45.596 1.00 0.00 C ATOM 1441 CG PRO A 198 -2.723 32.625 44.262 1.00 0.00 C ATOM 1442 CD PRO A 198 -3.140 31.566 43.253 1.00 0.00 C ATOM 1443 N LEU A 199 -6.299 31.894 46.637 1.00 0.00 N ATOM 1444 CA LEU A 199 -7.437 32.667 47.151 1.00 0.00 C ATOM 1445 C LEU A 199 -6.999 33.583 48.291 1.00 0.00 C ATOM 1446 O LEU A 199 -6.600 33.090 49.356 1.00 0.00 O ATOM 1447 CB LEU A 199 -8.544 31.744 47.654 1.00 0.00 C ATOM 1448 CG LEU A 199 -9.767 32.520 48.143 1.00 0.00 C ATOM 1449 CD1 LEU A 199 -10.504 33.210 46.996 1.00 0.00 C ATOM 1450 CD2 LEU A 199 -10.709 31.642 48.961 1.00 0.00 C ATOM 1451 N HIS A 200 -6.676 34.796 47.878 1.00 0.00 N ATOM 1452 CA HIS A 200 -6.192 35.858 48.767 1.00 0.00 C ATOM 1453 C HIS A 200 -7.309 36.438 49.625 1.00 0.00 C ATOM 1454 O HIS A 200 -8.054 37.300 49.147 1.00 0.00 O ATOM 1455 CB HIS A 200 -5.633 37.006 47.932 1.00 0.00 C ATOM 1456 CG HIS A 200 -4.619 36.524 46.886 1.00 0.00 C ATOM 1457 ND1 HIS A 200 -3.319 36.246 47.201 1.00 0.00 N ATOM 1458 CD2 HIS A 200 -4.789 36.321 45.569 1.00 0.00 C ATOM 1459 CE1 HIS A 200 -2.685 35.859 46.054 1.00 0.00 C ATOM 1460 NE2 HIS A 200 -3.602 35.907 45.041 1.00 0.00 N ATOM 1461 N CYS A 201 -7.188 36.237 50.922 1.00 0.00 N ATOM 1462 CA CYS A 201 -8.180 36.763 51.868 1.00 0.00 C ATOM 1463 C CYS A 201 -7.609 37.810 52.825 1.00 0.00 C ATOM 1464 O CYS A 201 -6.513 37.639 53.376 1.00 0.00 O ATOM 1465 CB CYS A 201 -8.815 35.618 52.645 1.00 0.00 C ATOM 1466 SG CYS A 201 -9.670 34.369 51.655 1.00 0.00 S ATOM 1467 N LEU A 202 -8.376 38.877 52.991 1.00 0.00 N ATOM 1468 CA LEU A 202 -7.975 40.044 53.790 1.00 0.00 C ATOM 1469 C LEU A 202 -8.280 39.863 55.276 1.00 0.00 C ATOM 1470 O LEU A 202 -9.455 39.775 55.655 1.00 0.00 O ATOM 1471 CB LEU A 202 -8.685 41.291 53.250 1.00 0.00 C ATOM 1472 CG LEU A 202 -8.063 42.621 53.695 1.00 0.00 C ATOM 1473 CD1 LEU A 202 -8.541 43.154 55.046 1.00 0.00 C ATOM 1474 CD2 LEU A 202 -6.549 42.680 53.510 1.00 0.00 C ATOM 1475 N VAL A 203 -7.249 39.438 55.988 1.00 0.00 N ATOM 1476 CA VAL A 203 -7.295 39.281 57.449 1.00 0.00 C ATOM 1477 C VAL A 203 -6.252 40.169 58.130 1.00 0.00 C ATOM 1478 O VAL A 203 -5.056 40.021 57.848 1.00 0.00 O ATOM 1479 CB VAL A 203 -7.062 37.812 57.817 1.00 0.00 C ATOM 1480 CG1 VAL A 203 -7.144 37.554 59.322 1.00 0.00 C ATOM 1481 CG2 VAL A 203 -8.004 36.880 57.058 1.00 0.00 C ATOM 1482 N ASN A 204 -6.697 40.854 59.182 1.00 0.00 N ATOM 1483 CA ASN A 204 -5.897 41.790 59.991 1.00 0.00 C ATOM 1484 C ASN A 204 -5.081 42.774 59.159 1.00 0.00 C ATOM 1485 O ASN A 204 -3.854 42.834 59.311 1.00 0.00 O ATOM 1486 CB ASN A 204 -4.991 41.061 60.984 1.00 0.00 C ATOM 1487 CG ASN A 204 -5.842 40.362 62.041 1.00 0.00 C ATOM 1488 OD1 ASN A 204 -5.579 39.206 62.394 1.00 0.00 O ATOM 1489 ND2 ASN A 204 -6.869 41.067 62.489 1.00 0.00 N ATOM 1490 N GLY A 205 -5.709 43.174 58.067 1.00 0.00 N ATOM 1491 CA GLY A 205 -5.157 44.163 57.133 1.00 0.00 C ATOM 1492 C GLY A 205 -4.110 43.563 56.201 1.00 0.00 C ATOM 1493 O GLY A 205 -3.296 44.295 55.624 1.00 0.00 O ATOM 1494 N GLN A 206 -3.997 42.248 56.279 1.00 0.00 N ATOM 1495 CA GLN A 206 -3.004 41.513 55.485 1.00 0.00 C ATOM 1496 C GLN A 206 -3.621 40.412 54.623 1.00 0.00 C ATOM 1497 O GLN A 206 -4.599 39.779 55.035 1.00 0.00 O ATOM 1498 CB GLN A 206 -1.994 40.898 56.453 1.00 0.00 C ATOM 1499 CG GLN A 206 -0.800 40.249 55.757 1.00 0.00 C ATOM 1500 CD GLN A 206 0.038 39.528 56.807 1.00 0.00 C ATOM 1501 OE1 GLN A 206 1.268 39.667 56.837 1.00 0.00 O ATOM 1502 NE2 GLN A 206 -0.638 38.666 57.549 1.00 0.00 N ATOM 1503 N TYR A 207 -3.199 40.371 53.368 1.00 0.00 N ATOM 1504 CA TYR A 207 -3.616 39.319 52.431 1.00 0.00 C ATOM 1505 C TYR A 207 -2.841 38.017 52.613 1.00 0.00 C ATOM 1506 O TYR A 207 -1.609 38.042 52.734 1.00 0.00 O ATOM 1507 CB TYR A 207 -3.484 39.776 50.979 1.00 0.00 C ATOM 1508 CG TYR A 207 -4.634 40.703 50.560 1.00 0.00 C ATOM 1509 CD1 TYR A 207 -5.899 40.174 50.359 1.00 0.00 C ATOM 1510 CD2 TYR A 207 -4.407 42.055 50.358 1.00 0.00 C ATOM 1511 CE1 TYR A 207 -6.956 41.001 49.967 1.00 0.00 C ATOM 1512 CE2 TYR A 207 -5.459 42.892 49.965 1.00 0.00 C ATOM 1513 CZ TYR A 207 -6.733 42.361 49.772 1.00 0.00 C ATOM 1514 OH TYR A 207 -7.789 43.196 49.474 1.00 0.00 O ATOM 1515 N ALA A 208 -3.591 36.997 52.992 1.00 0.00 N ATOM 1516 CA ALA A 208 -3.049 35.640 53.147 1.00 0.00 C ATOM 1517 C ALA A 208 -3.725 34.632 52.219 1.00 0.00 C ATOM 1518 O ALA A 208 -4.833 34.884 51.731 1.00 0.00 O ATOM 1519 CB ALA A 208 -3.162 35.177 54.597 1.00 0.00 C ATOM 1520 N VAL A 209 -2.936 33.669 51.776 1.00 0.00 N ATOM 1521 CA VAL A 209 -3.412 32.638 50.844 1.00 0.00 C ATOM 1522 C VAL A 209 -4.153 31.509 51.555 1.00 0.00 C ATOM 1523 O VAL A 209 -3.523 30.674 52.216 1.00 0.00 O ATOM 1524 CB VAL A 209 -2.243 32.075 50.037 1.00 0.00 C ATOM 1525 CG1 VAL A 209 -2.687 30.980 49.068 1.00 0.00 C ATOM 1526 CG2 VAL A 209 -1.478 33.181 49.313 1.00 0.00 C ATOM 1527 N HIS A 210 -5.445 31.735 51.715 1.00 0.00 N ATOM 1528 CA HIS A 210 -6.330 30.784 52.405 1.00 0.00 C ATOM 1529 C HIS A 210 -6.802 29.614 51.545 1.00 0.00 C ATOM 1530 O HIS A 210 -7.131 28.547 52.081 1.00 0.00 O ATOM 1531 CB HIS A 210 -7.547 31.499 52.989 1.00 0.00 C ATOM 1532 CG HIS A 210 -7.220 32.216 54.308 1.00 0.00 C ATOM 1533 ND1 HIS A 210 -7.571 31.687 55.519 1.00 0.00 N ATOM 1534 CD2 HIS A 210 -6.607 33.392 54.525 1.00 0.00 C ATOM 1535 CE1 HIS A 210 -7.157 32.552 56.493 1.00 0.00 C ATOM 1536 NE2 HIS A 210 -6.555 33.610 55.872 1.00 0.00 N ATOM 1537 N GLY A 211 -6.720 29.780 50.233 1.00 0.00 N ATOM 1538 CA GLY A 211 -7.253 28.752 49.323 1.00 0.00 C ATOM 1539 C GLY A 211 -6.386 28.407 48.113 1.00 0.00 C ATOM 1540 O GLY A 211 -5.500 29.183 47.734 1.00 0.00 O ATOM 1541 N VAL A 212 -6.486 27.134 47.739 1.00 0.00 N ATOM 1542 CA VAL A 212 -5.841 26.535 46.557 1.00 0.00 C ATOM 1543 C VAL A 212 -6.881 25.963 45.593 1.00 0.00 C ATOM 1544 O VAL A 212 -7.574 25.007 45.964 1.00 0.00 O ATOM 1545 CB VAL A 212 -4.893 25.413 46.990 1.00 0.00 C ATOM 1546 CG1 VAL A 212 -4.279 24.675 45.803 1.00 0.00 C ATOM 1547 CG2 VAL A 212 -3.818 25.895 47.960 1.00 0.00 C ATOM 1548 N THR A 213 -7.177 26.756 44.561 1.00 0.00 N ATOM 1549 CA THR A 213 -8.192 26.452 43.530 1.00 0.00 C ATOM 1550 C THR A 213 -8.234 24.983 43.122 1.00 0.00 C ATOM 1551 O THR A 213 -7.202 24.415 42.744 1.00 0.00 O ATOM 1552 CB THR A 213 -7.993 27.295 42.273 1.00 0.00 C ATOM 1553 OG1 THR A 213 -7.794 28.664 42.602 1.00 0.00 O ATOM 1554 CG2 THR A 213 -9.155 27.154 41.291 1.00 0.00 C ATOM 1555 N SER A 214 -9.288 24.330 43.566 1.00 0.00 N ATOM 1556 CA SER A 214 -9.451 22.904 43.287 1.00 0.00 C ATOM 1557 C SER A 214 -10.379 22.606 42.112 1.00 0.00 C ATOM 1558 O SER A 214 -9.925 22.064 41.097 1.00 0.00 O ATOM 1559 CB SER A 214 -9.926 22.170 44.535 1.00 0.00 C ATOM 1560 OG SER A 214 -9.912 20.776 44.267 1.00 0.00 O ATOM 1561 N PHE A 215 -11.672 22.837 42.314 1.00 0.00 N ATOM 1562 CA PHE A 215 -12.677 22.533 41.278 1.00 0.00 C ATOM 1563 C PHE A 215 -13.874 23.481 41.194 1.00 0.00 C ATOM 1564 O PHE A 215 -13.972 24.445 41.966 1.00 0.00 O ATOM 1565 CB PHE A 215 -13.158 21.077 41.361 1.00 0.00 C ATOM 1566 CG PHE A 215 -13.870 20.728 42.682 1.00 0.00 C ATOM 1567 CD1 PHE A 215 -13.140 20.258 43.761 1.00 0.00 C ATOM 1568 CD2 PHE A 215 -15.250 20.818 42.775 1.00 0.00 C ATOM 1569 CE1 PHE A 215 -13.781 19.931 44.961 1.00 0.00 C ATOM 1570 CE2 PHE A 215 -15.900 20.493 43.971 1.00 0.00 C ATOM 1571 CZ PHE A 215 -15.164 20.054 45.070 1.00 0.00 C ATOM 1572 N VAL A 216 -14.553 23.353 40.059 1.00 0.00 N ATOM 1573 CA VAL A 216 -15.833 24.009 39.746 1.00 0.00 C ATOM 1574 C VAL A 216 -16.885 22.989 39.316 1.00 0.00 C ATOM 1575 O VAL A 216 -16.586 21.792 39.217 1.00 0.00 O ATOM 1576 CB VAL A 216 -15.668 25.055 38.642 1.00 0.00 C ATOM 1577 CG1 VAL A 216 -14.934 26.305 39.121 1.00 0.00 C ATOM 1578 CG2 VAL A 216 -15.067 24.480 37.361 1.00 0.00 C ATOM 1579 N SER A 217 -18.072 23.482 39.004 1.00 0.00 N ATOM 1580 CA SER A 217 -19.162 22.613 38.554 1.00 0.00 C ATOM 1581 C SER A 217 -18.997 22.147 37.114 1.00 0.00 C ATOM 1582 O SER A 217 -18.401 22.869 36.305 1.00 0.00 O ATOM 1583 CB SER A 217 -20.510 23.311 38.680 1.00 0.00 C ATOM 1584 OG SER A 217 -21.483 22.497 38.034 1.00 0.00 O ATOM 1585 N ARG A 217A -19.150 20.847 36.961 1.00 0.00 N ATOM 1586 CA ARG A 217A -19.144 20.189 35.649 1.00 0.00 C ATOM 1587 C ARG A 217A -20.059 20.876 34.638 1.00 0.00 C ATOM 1588 O ARG A 217A -19.718 20.954 33.452 1.00 0.00 O ATOM 1589 CB ARG A 217A -19.561 18.731 35.799 1.00 0.00 C ATOM 1590 CG ARG A 217A -18.456 17.855 36.384 1.00 0.00 C ATOM 1591 CD ARG A 217A -18.974 16.461 36.734 1.00 0.00 C ATOM 1592 NE ARG A 217A -19.810 15.942 35.642 1.00 0.00 N ATOM 1593 CZ ARG A 217A -21.068 15.561 35.822 1.00 0.00 C ATOM 1594 NH1 ARG A 217A -21.782 15.130 34.795 1.00 0.00 N ATOM 1595 NH2 ARG A 217A -21.540 15.420 37.052 1.00 0.00 N ATOM 1596 N LEU A 218 -21.080 21.536 35.166 1.00 0.00 N ATOM 1597 CA LEU A 218 -22.049 22.288 34.356 1.00 0.00 C ATOM 1598 C LEU A 218 -21.442 23.565 33.789 1.00 0.00 C ATOM 1599 O LEU A 218 -21.952 24.124 32.810 1.00 0.00 O ATOM 1600 CB LEU A 218 -23.260 22.697 35.191 1.00 0.00 C ATOM 1601 CG LEU A 218 -24.101 21.514 35.656 1.00 0.00 C ATOM 1602 CD1 LEU A 218 -25.254 21.979 36.543 1.00 0.00 C ATOM 1603 CD2 LEU A 218 -24.602 20.679 34.479 1.00 0.00 C ATOM 1604 N GLY A 219 -20.315 23.938 34.365 1.00 0.00 N ATOM 1605 CA GLY A 219 -19.635 25.181 33.986 1.00 0.00 C ATOM 1606 C GLY A 219 -18.971 25.878 35.170 1.00 0.00 C ATOM 1607 O GLY A 219 -19.245 25.538 36.328 1.00 0.00 O ATOM 1608 N CYS A 220 -18.288 26.959 34.853 1.00 0.00 N ATOM 1609 CA CYS A 220 -17.486 27.709 35.824 1.00 0.00 C ATOM 1610 C CYS A 220 -18.290 28.653 36.709 1.00 0.00 C ATOM 1611 O CYS A 220 -18.278 28.523 37.939 1.00 0.00 O ATOM 1612 CB CYS A 220 -16.382 28.462 35.089 1.00 0.00 C ATOM 1613 SG CYS A 220 -15.121 27.385 34.380 1.00 0.00 S ATOM 1614 N ASN A 221 -19.015 29.545 36.070 1.00 0.00 N ATOM 1615 CA ASN A 221 -19.808 30.538 36.799 1.00 0.00 C ATOM 1616 C ASN A 221 -21.286 30.171 36.928 1.00 0.00 C ATOM 1617 O ASN A 221 -22.086 30.385 36.009 1.00 0.00 O ATOM 1618 CB ASN A 221 -19.582 31.952 36.260 1.00 0.00 C ATOM 1619 CG ASN A 221 -19.951 32.039 34.781 1.00 0.00 C ATOM 1620 OD1 ASN A 221 -19.361 31.340 33.945 1.00 0.00 O ATOM 1621 ND2 ASN A 221 -21.118 32.622 34.567 1.00 0.00 N ATOM 1622 N VAL A 221A -21.502 29.243 37.842 1.00 0.00 N ATOM 1623 CA VAL A 221A -22.849 28.724 38.123 1.00 0.00 C ATOM 1624 C VAL A 221A -23.379 29.122 39.500 1.00 0.00 C ATOM 1625 O VAL A 221A -22.602 29.156 40.463 1.00 0.00 O ATOM 1626 CB VAL A 221A -22.883 27.203 37.951 1.00 0.00 C ATOM 1627 CG1 VAL A 221A -24.223 26.594 38.358 1.00 0.00 C ATOM 1628 CG2 VAL A 221A -22.490 26.777 36.538 1.00 0.00 C ATOM 1629 N THR A 222 -24.493 29.839 39.441 1.00 0.00 N ATOM 1630 CA THR A 222 -25.244 30.295 40.617 1.00 0.00 C ATOM 1631 C THR A 222 -25.478 29.162 41.616 1.00 0.00 C ATOM 1632 O THR A 222 -25.818 28.047 41.201 1.00 0.00 O ATOM 1633 CB THR A 222 -26.581 30.875 40.164 1.00 0.00 C ATOM 1634 OG1 THR A 222 -26.372 31.717 39.035 1.00 0.00 O ATOM 1635 CG2 THR A 222 -27.287 31.659 41.269 1.00 0.00 C ATOM 1636 N ARG A 223 -24.897 29.369 42.790 1.00 0.00 N ATOM 1637 CA ARG A 223 -24.900 28.425 43.924 1.00 0.00 C ATOM 1638 C ARG A 223 -23.943 27.257 43.767 1.00 0.00 C ATOM 1639 O ARG A 223 -24.206 26.168 44.292 1.00 0.00 O ATOM 1640 CB ARG A 223 -26.277 27.936 44.356 1.00 0.00 C ATOM 1641 CG ARG A 223 -27.021 29.022 45.114 1.00 0.00 C ATOM 1642 CD ARG A 223 -28.455 28.621 45.429 1.00 0.00 C ATOM 1643 NE ARG A 223 -29.259 29.844 45.414 1.00 0.00 N ATOM 1644 CZ ARG A 223 -29.881 30.249 44.318 1.00 0.00 C ATOM 1645 NH1 ARG A 223 -30.536 31.398 44.337 1.00 0.00 N ATOM 1646 NH2 ARG A 223 -30.199 29.351 43.395 1.00 0.00 N ATOM 1647 N LYS A 224 -23.084 27.404 42.781 1.00 0.00 N ATOM 1648 CA LYS A 224 -21.953 26.478 42.658 1.00 0.00 C ATOM 1649 C LYS A 224 -20.602 27.181 42.777 1.00 0.00 C ATOM 1650 O LYS A 224 -19.892 27.288 41.770 1.00 0.00 O ATOM 1651 CB LYS A 224 -22.026 25.701 41.345 1.00 0.00 C ATOM 1652 CG LYS A 224 -23.179 24.701 41.346 1.00 0.00 C ATOM 1653 CD LYS A 224 -22.955 23.584 42.364 1.00 0.00 C ATOM 1654 CE LYS A 224 -24.202 22.728 42.561 1.00 0.00 C ATOM 1655 NZ LYS A 224 -25.267 23.541 43.171 1.00 0.00 N ATOM 1656 N PRO A 225 -20.231 27.608 43.989 1.00 0.00 N ATOM 1657 CA PRO A 225 -19.018 28.417 44.223 1.00 0.00 C ATOM 1658 C PRO A 225 -17.720 27.642 44.020 1.00 0.00 C ATOM 1659 O PRO A 225 -17.738 26.411 43.896 1.00 0.00 O ATOM 1660 CB PRO A 225 -19.108 28.887 45.672 1.00 0.00 C ATOM 1661 CG PRO A 225 -19.983 27.855 46.353 1.00 0.00 C ATOM 1662 CD PRO A 225 -20.969 27.453 45.266 1.00 0.00 C ATOM 1663 N THR A 226 -16.703 28.396 43.647 1.00 0.00 N ATOM 1664 CA THR A 226 -15.370 27.830 43.430 1.00 0.00 C ATOM 1665 C THR A 226 -14.821 27.236 44.725 1.00 0.00 C ATOM 1666 O THR A 226 -15.121 27.766 45.803 1.00 0.00 O ATOM 1667 CB THR A 226 -14.427 28.905 42.890 1.00 0.00 C ATOM 1668 OG1 THR A 226 -15.031 29.544 41.768 1.00 0.00 O ATOM 1669 CG2 THR A 226 -13.070 28.336 42.476 1.00 0.00 C ATOM 1670 N VAL A 227 -14.520 25.953 44.632 1.00 0.00 N ATOM 1671 CA VAL A 227 -14.021 25.202 45.789 1.00 0.00 C ATOM 1672 C VAL A 227 -12.497 25.130 45.854 1.00 0.00 C ATOM 1673 O VAL A 227 -11.842 24.956 44.818 1.00 0.00 O ATOM 1674 CB VAL A 227 -14.626 23.801 45.814 1.00 0.00 C ATOM 1675 CG1 VAL A 227 -14.194 23.028 47.056 1.00 0.00 C ATOM 1676 CG2 VAL A 227 -16.147 23.853 45.711 1.00 0.00 C ATOM 1677 N PHE A 228 -12.006 25.663 46.966 1.00 0.00 N ATOM 1678 CA PHE A 228 -10.579 25.770 47.296 1.00 0.00 C ATOM 1679 C PHE A 228 -10.156 24.770 48.371 1.00 0.00 C ATOM 1680 O PHE A 228 -10.978 24.345 49.191 1.00 0.00 O ATOM 1681 CB PHE A 228 -10.284 27.176 47.827 1.00 0.00 C ATOM 1682 CG PHE A 228 -10.702 28.289 46.851 1.00 0.00 C ATOM 1683 CD1 PHE A 228 -9.832 28.710 45.861 1.00 0.00 C ATOM 1684 CD2 PHE A 228 -11.937 28.902 46.987 1.00 0.00 C ATOM 1685 CE1 PHE A 228 -10.211 29.724 44.973 1.00 0.00 C ATOM 1686 CE2 PHE A 228 -12.323 29.913 46.102 1.00 0.00 C ATOM 1687 CZ PHE A 228 -11.461 30.324 45.090 1.00 0.00 C ATOM 1688 N THR A 229 -8.883 24.415 48.346 1.00 0.00 N ATOM 1689 CA THR A 229 -8.266 23.551 49.361 1.00 0.00 C ATOM 1690 C THR A 229 -7.776 24.401 50.531 1.00 0.00 C ATOM 1691 O THR A 229 -7.123 25.423 50.281 1.00 0.00 O ATOM 1692 CB THR A 229 -7.087 22.799 48.738 1.00 0.00 C ATOM 1693 OG1 THR A 229 -7.532 22.064 47.601 1.00 0.00 O ATOM 1694 CG2 THR A 229 -6.406 21.849 49.720 1.00 0.00 C ATOM 1695 N ARG A 230 -8.495 24.254 51.641 1.00 0.00 N ATOM 1696 CA ARG A 230 -8.268 25.051 52.862 1.00 0.00 C ATOM 1697 C ARG A 230 -6.864 24.904 53.445 1.00 0.00 C ATOM 1698 O ARG A 230 -6.626 23.985 54.237 1.00 0.00 O ATOM 1699 CB ARG A 230 -9.276 24.678 53.945 1.00 0.00 C ATOM 1700 CG ARG A 230 -9.415 25.786 54.986 1.00 0.00 C ATOM 1701 CD ARG A 230 -10.323 25.399 56.149 1.00 0.00 C ATOM 1702 NE ARG A 230 -9.541 24.737 57.201 1.00 0.00 N ATOM 1703 CZ ARG A 230 -9.959 23.697 57.910 1.00 0.00 C ATOM 1704 NH1 ARG A 230 -9.191 23.230 58.883 1.00 0.00 N ATOM 1705 NH2 ARG A 230 -11.119 23.105 57.639 1.00 0.00 N ATOM 1706 N VAL A 231 -5.956 25.721 52.925 1.00 0.00 N ATOM 1707 CA VAL A 231 -4.528 25.771 53.300 1.00 0.00 C ATOM 1708 C VAL A 231 -4.231 25.638 54.795 1.00 0.00 C ATOM 1709 O VAL A 231 -3.372 24.831 55.177 1.00 0.00 O ATOM 1710 CB VAL A 231 -3.899 27.059 52.764 1.00 0.00 C ATOM 1711 CG1 VAL A 231 -2.443 27.230 53.196 1.00 0.00 C ATOM 1712 CG2 VAL A 231 -4.043 27.170 51.250 1.00 0.00 C ATOM 1713 N SER A 232 -5.151 26.158 55.596 1.00 0.00 N ATOM 1714 CA SER A 232 -4.977 26.212 57.056 1.00 0.00 C ATOM 1715 C SER A 232 -5.098 24.838 57.706 1.00 0.00 C ATOM 1716 O SER A 232 -4.728 24.657 58.871 1.00 0.00 O ATOM 1717 CB SER A 232 -6.019 27.128 57.684 1.00 0.00 C ATOM 1718 OG SER A 232 -7.260 26.435 57.738 1.00 0.00 O ATOM 1719 N ALA A 233 -5.603 23.899 56.930 1.00 0.00 N ATOM 1720 CA ALA A 233 -5.769 22.521 57.405 1.00 0.00 C ATOM 1721 C ALA A 233 -4.496 21.705 57.232 1.00 0.00 C ATOM 1722 O ALA A 233 -4.422 20.562 57.702 1.00 0.00 O ATOM 1723 CB ALA A 233 -6.883 21.827 56.624 1.00 0.00 C ATOM 1724 N TYR A 234 -3.665 22.187 56.327 1.00 0.00 N ATOM 1725 CA TYR A 234 -2.479 21.431 55.906 1.00 0.00 C ATOM 1726 C TYR A 234 -1.153 22.007 56.394 1.00 0.00 C ATOM 1727 O TYR A 234 -0.100 21.536 55.950 1.00 0.00 O ATOM 1728 CB TYR A 234 -2.452 21.282 54.382 1.00 0.00 C ATOM 1729 CG TYR A 234 -3.668 20.495 53.865 1.00 0.00 C ATOM 1730 CD1 TYR A 234 -4.770 21.170 53.363 1.00 0.00 C ATOM 1731 CD2 TYR A 234 -3.657 19.109 53.884 1.00 0.00 C ATOM 1732 CE1 TYR A 234 -5.883 20.459 52.899 1.00 0.00 C ATOM 1733 CE2 TYR A 234 -4.765 18.389 53.417 1.00 0.00 C ATOM 1734 CZ TYR A 234 -5.879 19.069 52.927 1.00 0.00 C ATOM 1735 OH TYR A 234 -7.012 18.375 52.554 1.00 0.00 O ATOM 1736 N ILE A 235 -1.241 23.135 57.089 1.00 0.00 N ATOM 1737 CA ILE A 235 -0.066 23.873 57.598 1.00 0.00 C ATOM 1738 C ILE A 235 1.030 22.986 58.190 1.00 0.00 C ATOM 1739 O ILE A 235 2.159 22.999 57.679 1.00 0.00 O ATOM 1740 CB ILE A 235 -0.482 24.942 58.609 1.00 0.00 C ATOM 1741 CG1 ILE A 235 -1.458 25.951 58.007 1.00 0.00 C ATOM 1742 CG2 ILE A 235 0.723 25.642 59.238 1.00 0.00 C ATOM 1743 CD1 ILE A 235 -0.849 26.726 56.840 1.00 0.00 C ATOM 1744 N SER A 236 0.572 21.997 58.945 1.00 0.00 N ATOM 1745 CA SER A 236 1.436 21.014 59.615 1.00 0.00 C ATOM 1746 C SER A 236 2.245 20.183 58.630 1.00 0.00 C ATOM 1747 O SER A 236 3.482 20.194 58.669 1.00 0.00 O ATOM 1748 CB SER A 236 0.590 20.048 60.436 1.00 0.00 C ATOM 1749 OG SER A 236 1.420 18.958 60.826 1.00 0.00 O ATOM 1750 N TRP A 237 1.518 19.752 57.621 1.00 0.00 N ATOM 1751 CA TRP A 237 2.047 18.909 56.548 1.00 0.00 C ATOM 1752 C TRP A 237 3.046 19.672 55.686 1.00 0.00 C ATOM 1753 O TRP A 237 4.218 19.274 55.637 1.00 0.00 O ATOM 1754 CB TRP A 237 0.881 18.398 55.698 1.00 0.00 C ATOM 1755 CG TRP A 237 1.351 17.542 54.512 1.00 0.00 C ATOM 1756 CD1 TRP A 237 1.782 16.265 54.489 1.00 0.00 C ATOM 1757 CD2 TRP A 237 1.391 17.963 53.182 1.00 0.00 C ATOM 1758 NE1 TRP A 237 2.126 15.901 53.205 1.00 0.00 N ATOM 1759 CE2 TRP A 237 1.919 16.889 52.426 1.00 0.00 C ATOM 1760 CE3 TRP A 237 1.057 19.175 52.595 1.00 0.00 C ATOM 1761 CZ2 TRP A 237 2.192 16.983 51.071 1.00 0.00 C ATOM 1762 CZ3 TRP A 237 1.301 19.266 51.218 1.00 0.00 C ATOM 1763 CH2 TRP A 237 1.855 18.209 50.482 1.00 0.00 C ATOM 1764 N ILE A 238 2.679 20.924 55.449 1.00 0.00 N ATOM 1765 CA ILE A 238 3.467 21.828 54.600 1.00 0.00 C ATOM 1766 C ILE A 238 4.837 22.114 55.202 1.00 0.00 C ATOM 1767 O ILE A 238 5.844 21.752 54.577 1.00 0.00 O ATOM 1768 CB ILE A 238 2.710 23.133 54.343 1.00 0.00 C ATOM 1769 CG1 ILE A 238 1.443 22.914 53.518 1.00 0.00 C ATOM 1770 CG2 ILE A 238 3.599 24.216 53.736 1.00 0.00 C ATOM 1771 CD1 ILE A 238 0.635 24.200 53.350 1.00 0.00 C ATOM 1772 N ASN A 239 4.798 22.142 56.525 1.00 0.00 N ATOM 1773 CA ASN A 239 6.009 22.405 57.310 1.00 0.00 C ATOM 1774 C ASN A 239 6.911 21.184 57.429 1.00 0.00 C ATOM 1775 O ASN A 239 8.066 21.255 56.990 1.00 0.00 O ATOM 1776 CB ASN A 239 5.678 22.964 58.691 1.00 0.00 C ATOM 1777 CG ASN A 239 5.203 24.405 58.540 1.00 0.00 C ATOM 1778 OD1 ASN A 239 4.407 24.895 59.351 1.00 0.00 O ATOM 1779 ND2 ASN A 239 5.795 25.081 57.567 1.00 0.00 N ATOM 1780 N ASN A 240 6.242 20.049 57.573 1.00 0.00 N ATOM 1781 CA ASN A 240 6.926 18.753 57.716 1.00 0.00 C ATOM 1782 C ASN A 240 7.677 18.342 56.456 1.00 0.00 C ATOM 1783 O ASN A 240 8.901 18.161 56.513 1.00 0.00 O ATOM 1784 CB ASN A 240 5.955 17.640 58.112 1.00 0.00 C ATOM 1785 CG ASN A 240 5.553 17.800 59.575 1.00 0.00 C ATOM 1786 OD1 ASN A 240 4.428 17.455 59.961 1.00 0.00 O ATOM 1787 ND2 ASN A 240 6.463 18.379 60.341 1.00 0.00 N ATOM 1788 N VAL A 241 7.039 18.674 55.349 1.00 0.00 N ATOM 1789 CA VAL A 241 7.567 18.341 54.021 1.00 0.00 C ATOM 1790 C VAL A 241 8.770 19.194 53.641 1.00 0.00 C ATOM 1791 O VAL A 241 9.872 18.642 53.502 1.00 0.00 O ATOM 1792 CB VAL A 241 6.473 18.455 52.960 1.00 0.00 C ATOM 1793 CG1 VAL A 241 7.025 18.479 51.535 1.00 0.00 C ATOM 1794 CG2 VAL A 241 5.414 17.373 53.139 1.00 0.00 C ATOM 1795 N ILE A 242 8.636 20.454 54.015 1.00 0.00 N ATOM 1796 CA ILE A 242 9.659 21.451 53.691 1.00 0.00 C ATOM 1797 C ILE A 242 10.902 21.329 54.565 1.00 0.00 C ATOM 1798 O ILE A 242 12.007 21.246 54.013 1.00 0.00 O ATOM 1799 CB ILE A 242 9.075 22.864 53.724 1.00 0.00 C ATOM 1800 CG1 ILE A 242 8.142 23.125 52.543 1.00 0.00 C ATOM 1801 CG2 ILE A 242 10.133 23.955 53.880 1.00 0.00 C ATOM 1802 CD1 ILE A 242 7.641 24.568 52.510 1.00 0.00 C ATOM 1803 N ALA A 243 10.660 20.758 55.732 1.00 0.00 N ATOM 1804 CA ALA A 243 11.732 20.603 56.722 1.00 0.00 C ATOM 1805 C ALA A 243 12.482 19.286 56.563 1.00 0.00 C ATOM 1806 O ALA A 243 13.689 19.216 56.825 1.00 0.00 O ATOM 1807 CB ALA A 243 11.179 20.711 58.139 1.00 0.00 C ATOM 1808 N SER A 244 11.809 18.345 55.934 1.00 0.00 N ATOM 1809 CA SER A 244 12.417 17.035 55.692 1.00 0.00 C ATOM 1810 C SER A 244 13.036 16.986 54.303 1.00 0.00 C ATOM 1811 O SER A 244 13.154 15.899 53.724 1.00 0.00 O ATOM 1812 CB SER A 244 11.366 15.938 55.806 1.00 0.00 C ATOM 1813 OG SER A 244 10.378 16.162 54.808 1.00 0.00 O ATOM 1814 N ASN A 245 12.943 18.148 53.670 1.00 0.00 N ATOM 1815 CA ASN A 245 13.496 18.377 52.324 1.00 0.00 C ATOM 1816 C ASN A 245 14.439 19.571 52.232 1.00 0.00 C ATOM 1817 O ASN A 245 14.421 20.270 51.213 1.00 0.00 O ATOM 1818 CB ASN A 245 12.396 18.523 51.278 1.00 0.00 C ATOM 1819 CG ASN A 245 11.999 17.148 50.753 1.00 0.00 C ATOM 1820 OD1 ASN A 245 12.719 16.615 49.899 1.00 0.00 O ATOM 1821 ND2 ASN A 245 11.248 16.460 51.601 1.00 0.00 N ATOM 1822 OXT ASN A 245 15.222 19.801 53.161 1.00 0.00 O TER 1823 ASN A 245 HETATM 1824 S SO4 A 246 -8.300 21.800 60.900 1.00 0.00 S HETATM 1825 S TSU A 247 -8.299 23.390 37.426 1.00 0.00 S HETATM 1826 O2 TSU A 247 -9.721 23.151 37.607 1.00 0.00 O HETATM 1827 O3 TSU A 247 -8.087 24.591 36.631 1.00 0.00 O HETATM 1828 C1 TSU A 247 -7.585 22.020 36.603 1.00 0.00 C HETATM 1829 C2 TSU A 247 -6.545 22.217 35.689 1.00 0.00 C HETATM 1830 C3 TSU A 247 -5.969 21.121 35.034 1.00 0.00 C HETATM 1831 C4 TSU A 247 -6.435 19.824 35.280 1.00 0.00 C HETATM 1832 C5 TSU A 247 -7.498 19.635 36.172 1.00 0.00 C HETATM 1833 C6 TSU A 247 -8.075 20.730 36.830 1.00 0.00 C HETATM 1834 C7 TSU A 247 -5.482 18.657 35.033 1.00 0.00 C HETATM 1835 O HOH A 248 -18.700 26.100 40.100 1.00 0.00 O HETATM 1836 O HOH A 249 -19.400 30.200 40.400 1.00 0.00 O HETATM 1837 O HOH A 250 -21.000 32.200 40.100 1.00 0.00 O HETATM 1838 O HOH A 251 -17.800 31.500 42.000 1.00 0.00 O HETATM 1839 O HOH A 252 -16.100 27.400 53.300 1.00 0.00 O HETATM 1840 O HOH A 253 -16.500 24.800 53.400 1.00 0.00 O HETATM 1841 O HOH A 254 -16.100 31.300 55.300 1.00 0.00 O HETATM 1842 O HOH A 255 -13.900 29.100 55.600 1.00 0.00 O HETATM 1843 O HOH A 256 0.900 40.600 37.500 1.00 0.00 O HETATM 1844 O HOH A 257 4.400 40.700 37.300 1.00 0.00 O HETATM 1845 O HOH A 258 5.700 42.300 35.700 1.00 0.00 O HETATM 1846 O HOH A 259 3.800 39.600 39.900 1.00 0.00 O HETATM 1847 O HOH A 260 -6.400 30.900 41.800 1.00 0.00 O HETATM 1848 O HOH A 261 -4.400 30.900 39.600 1.00 0.00 O HETATM 1849 O HOH A 262 -3.800 30.400 36.400 1.00 0.00 O HETATM 1850 O HOH A 263 -1.900 28.200 45.600 1.00 0.00 O HETATM 1851 O HOH A 264 -9.600 29.500 56.100 1.00 0.00 O HETATM 1852 O HOH A 265 -7.100 28.500 54.700 1.00 0.00 O HETATM 1853 O HOH A 266 -9.600 18.600 46.400 1.00 0.00 O HETATM 1854 O HOH A 267 -9.200 19.600 48.300 1.00 0.00 O HETATM 1855 O HOH A 268 -8.900 18.800 51.100 1.00 0.00 O HETATM 1856 O HOH A 269 5.100 36.100 41.200 1.00 0.00 O HETATM 1857 O HOH A 270 4.400 35.100 38.200 1.00 0.00 O HETATM 1858 O HOH A 271 2.200 36.800 38.600 1.00 0.00 O HETATM 1859 O HOH A 272 5.200 37.800 30.100 1.00 0.00 O CONECT 231 352 CONECT 352 231 CONECT 980 1466 CONECT 1223 1341 CONECT 1341 1223 CONECT 1400 1613 CONECT 1466 980 CONECT 1613 1400 CONECT 1825 1826 1827 1828 CONECT 1826 1825 CONECT 1827 1825 CONECT 1828 1825 1829 1833 CONECT 1829 1828 1830 CONECT 1830 1829 1831 CONECT 1831 1830 1832 1834 CONECT 1832 1831 1833 CONECT 1833 1828 1832 CONECT 1834 1831 MASTER 433 1 2 2 17 0 4 6 1858 1 18 19 END